Roach's Introductory Clinical Pharmacology 11th Edition - Upper Gastrointestinal System Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Upper Gastrointestinal System Drugs related questions and content

A client is prescribed ranitidine. A review of the client's medication history reveals that she also takes warfarin for treatment of deep vein thrombosis. The nurse would monitor the client for which of the following?

  • A. Decreased white blood cell count
  • B. Increased risk of respiratory depression
  • C. Increased risk for bleeding
  • D. Decreased seizure threshold
Correct Answer: C

Rationale: Histamine-2 receptor antagonists when given with warfarin place the client at an increased risk for bleeding. A decreased white blood cell count occurs when histamine-2 receptor antagonists are given with carmustine. An increased risk of respiratory depression occurs when histamine-2 receptor antagonists are given with opioid analgesics. This class of drugs does not interact with any antiseizure medications.