A client is receiving atorvastatin. The nurse would be alert to client complaints of which of the following?
- A. Headache
- B. Sedation
- C. Insomnia
- D. Diarrhea
- E. Constipation
Correct Answer: A,C,E
Rationale: Atorvastatin is an HMG-CoA reductase inhibitor (statin). Adverse reactions of statins include headache, dizziness, insomnia, flatulence, abdominal pain, cramping, constipation, and nausea.
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A nurse is caring for a client receiving gemfibrozil. Which of the following would the nurse include in the teaching plan for this client?
- A. Take the drug along with meals
- B. Observe caution while driving
- C. Take a single dose once daily in the evening
- D. Be alert for mild to severe facial flushing
Correct Answer: B
Rationale: When preparing a teaching plan for the client receiving the fibric acid derivative gemfibrozil, the nurse should instruct the client to observe caution while driving. Rosuvastatin calcium is taken as a single dose once daily in the evening. The nurse instructs a client prescribed nicotinic acid to take it along with meals; it may also cause mild to severe facial flushing.
A nurse is explaining how statin drugs help lower cholesterol, LDL, and triglycerides. Which of the following would the nurse include in the explanation?
- A. Decreased absorption of cholesterol from the GI tract
- B. Promotion of cholesterol breakdown
- C. Formation of a substance that is excreted in the feces
- D. Decreased breakdown of fat to cholesterol
- E. Inhibition of cholesterol production
Correct Answer: A,B
Rationale: Statins inhibit the manufacture of cholesterol or promote the breakdown of cholesterol. The bile acid resins bind to bile acids to form an insoluble substance that cannot be absorbed by the intestine, so it is excreted in the feces.
The nurse is preparing a client for discharge. The client is prescribed antihyperlipidemic drug therapy. The nurse would include which of the following in the discharge teaching?
- A. Reason for taking the prescribed drug
- B. Drug name
- C. Correct dose
- D. Frequency of administration
- E. Dosage form
Correct Answer: A,B,C,D,E
Rationale: The nurse should review the reasons for the drug and prescribed therapy, including drug name, form and method of preparation, correct dose, and frequency of administration, as part of a client's discharge counseling.
A client is currently taking propranolol (Inderal) for hypertension, glipizide (Glucotrol) for diabetes, and acetaminophen (Tylenol) for osteoarthritis. If cholestyramine was given to this client, which of the following would likely result?
- A. The client would experience hypoglycemia from increased absorption of glipizide
- B. The client would experience decreased analgesia from decreased absorption of acetaminophen
- C. The client would experience an increase in blood pressure due to decreased absorption of propranolol
- D. The client would experience hypotension from increased absorption of propranolol
- E. The client would experience hyperglycemia from decreased absorption of glipizide
Correct Answer: C,E
Rationale: The use of bile acid resins, like cholestyramine, decreases the absorption of some medications including glipizide and propranolol. This decreased absorption could result in hyperglycemia and an increase in blood pressure for this particular client.
A client with hypercholesterolemia is prescribed lovastatin. When instructing the client how to take the drug, which of the following would the nurse include?
- A. Taking the drug with his evening meal
- B. Combining the drug with the artificial sweetener aspartame
- C. Mixing the drug with highly fluid soups or pulpy fruits
- D. Taking the drug with grapefruit juice
Correct Answer: A
Rationale: For the self-administration of lovastatin, the nurse should suggest the client take the drug with his evening meal. Cholestyramine powder is mixed with highly fluid soups or pulpy fruits. Cholestyramine is available combined with the artificial sweetener aspartame. The client should not drink grapefruit juice when taking lovastatin.
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