Nokea
A nurse is reviewing the medical record of a client who is prescribed statin therapy. The nurse understands that this class of drugs is contraindicated in clients with which of the following conditions?
- A. Kidney disease
- B. Pregnancy
- C. Serious hepatic disease
- D. Carcinoma of the breast
- E. Lactation
Correct Answer: B,C,E
Rationale: Statin drugs are contraindicated in individuals with known hypersensitivity to the drugs or serious liver disease and during pregnancy (category X) and lactation.
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A client with very high serum triglyceride levels is prescribed the fibric acid derivative clofibrate. The nurse understands that this drug would be contraindicated if the client has which condition?
- A. Endocrine disorder
- B. Primary biliary cirrhosis
- C. Arterial bleeding
- D. Respiratory depression
Correct Answer: B
Rationale: The fibric acid derivative clofibrate is contraindicated in clients with primary biliary cirrhosis. The use of clofibrate is not contraindicated in clients with an endocrine disorder. The HMG-CoA reductase inhibitors are used with caution in clients with a history of endocrine disorders. Niacin is contraindicated in clients with arterial bleeding. The fibric acid derivative clofibrate is not contraindicated in clients with respiratory depression.
After teaching a group of nursing students about bile acids, the instructor determines that the teaching was successful when the students identify which of the following as true about bile?
- A. Bile is manufactured by the gallbladder
- B. Bile is stored in the liver
- C. Bile emulsifies fat and lipids
- D. Bile is secreted by the liver
- E. Bile is classified as a hormone
Correct Answer: C,D
Rationale: Bile is manufactured and secreted by the liver and stored in the gallbladder, it emulsifies fat and lipids, and these products pass through the intestine.
The nurse discusses the benefit of adding a statin drug to a client's medication regimen based on the understanding that this group of drugs can reduce the risk of death from which of the following?
- A. Stroke
- B. Transient ischemic attack
- C. Kidney disease
- D. Hepatic disease
- E. Cancer
Correct Answer: A,B
Rationale: The use of statins in clients with hyperlipidemia with or without clinically evident coronary heart disease can reduce the risk of death from stroke and transient ischemic attacks.
After administering an antihyperlipidemic drug, the nurse continues to assess which of the following?
- A. Blood glucose
- B. Vital signs
- C. Assessment of bowel function
- D. Input and output
- E. Stool sample
Correct Answer: B,C
Rationale: Clients on antihyperlipidemic medications should have vital signs checked and bowel function assessed because an adverse reaction to these drugs is constipation. Constipation may become serious if not treated early in the medication regimen.
A client who is prescribed niacin comes to the clinic complaining of significant skin flushing and itching. The client states, 'It's really uncomfortable, so much so that I almost stopped taking the drug.' The nurse informs the primary health care provider. Which of the following would the nurse anticipate that the primary health care provider may recommend?
- A. Prednisone
- B. Aspirin
- C. Ibuprofen
- D. Hydrocortisone
Correct Answer: B
Rationale: Aspirin may be recommended before taking niacin preparations to reduce adverse reactions when niacin causes skin reactions that are severe or cause extreme discomfort.