A client is receiving streptokinase. The nurse understands that which of the following would occur? Select all that apply.
- A. Breakdown of existing thrombi
- B. Reopening of occluded blood vessels
- C. Prevention of tissue necrosis
- D. Decreased risk of internal bleeding
- E. Prevention of formation of a thrombus
Correct Answer: A,B,C
Rationale: Streptokinase is a thrombolytic drug. Thrombolytic drugs break down existing thrombi, reopen blood vessels after occlusion, and prevent tissue necrosis.
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A client is prescribed warfarin. The client also takes a diuretic for the treatment of cardiac problems. The nurse would anticipate which of the following?
- A. Decreased effectiveness of the anticoagulant
- B. Increased effectiveness of the diuretic
- C. Increased absorption of the anticoagulant
- D. Increased absorption of the diuretic
Correct Answer: A
Rationale: The nurse should monitor for decreased effectiveness of warfarin as an effect of the interaction between the anticoagulant and the diuretic.
A client with intermittent claudication is prescribed cilostazol by the primary health care provider. The nurse would expect to administer this drug cautiously if the client's history reveals which of the following?
- A. Intermittent claudication
- B. Pulmonary emboli
- C. Myocardial infarction
- D. Pancytopenia
Correct Answer: D
Rationale: The nurse should administer cilostazol with caution to clients with pancytopenia. Anticoagulants are used for the prevention and treatment of pulmonary emboli, the adjuvant treatment of myocardial infarction, and the treatment of intermittent claudication.
A female client is receiving an anticoagulant to prevent the formation and extension of blood clots. What instruction should the nurse include in the teaching plan for the client?
- A. Avoid caffeinated drinks.
- B. Take the drug on an empty stomach.
- C. Use a reliable contraceptive.
- D. Take the drug with a glass of milk.
Correct Answer: C
Rationale: The nurse should instruct the female client to use a reliable contraceptive to prevent pregnancy, as anticoagulants can pose risks during pregnancy.
Which of the following may be ordered periodically during therapy with anticoagulants? Select all that apply.
- A. Urinalysis
- B. Platelet count
- C. Blood count
- D. Stool analysis
- E. Ultrasound
Correct Answer: B,C,D
Rationale: A complete blood count, platelet count, and stool analysis for occult blood may be ordered periodically throughout anticoagulant therapy.
A client is being discharged on warfarin therapy. Which of the following would the nurse include in the teaching plan for the client? Select all that apply.
- A. Be consistent with your intake of foods containing vitamin K.
- B. Do not change brands of warfarin without consulting the physician.
- C. Take the drug at the same time every evening.
- D. Do not take or stop taking other medications except on the advice of the physician.
- E. Inform the dentist of therapy with warfarin prior to any treatment or procedure.
Correct Answer: A,B,C,D,E
Rationale: Instructions would include being consistent with intake of foods containing vitamin K, not changing brands of the drug, taking the drug at the same time each evening, not taking or stopping other medications, and informing the dentist about the use of warfarin.
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