When teaching a class about parenterally administered heparin, which of the following would the nurse include? Select all that apply.
- A. Onset of action is almost immediate.
- B. Maximum effect occurs within 10 minutes.
- C. It is preferably given intramuscularly.
- D. Clotting time returns to normal within 4 hours.
- E. It causes fewer adverse reactions than the oral form.
Correct Answer: A,B,D
Rationale: Parenteral heparin results in an almost immediate onset of action with a maximum effect within 10 minutes, but clotting returns to normal within 4 hours unless subsequent doses are given. It is preferably given subcutaneously or intravenously.
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Protamine is used to treat overdose of which of the following medications? Select all that apply.
- A. Clopidogrel (Plavix)
- B. Heparin
- C. Enoxaparin (Lovenox)
- D. Alreplase (Activase)
- E. Warfarin (Coumadin)
Correct Answer: B,C
Rationale: Protamine is used to treat overdose of heparin and low-molecular-weight heparins (LMWHs).
Which assessment would the nurse obtain before administering an anticoagulant to a client with DVT? Select all that apply.
- A. Test for a positive Homans' sign.
- B. Examine extremity for skin temperature.
- C. Assess pain.
- D. Assess blood pressure.
- E. Check for pedal pulse.
Correct Answer: A,B,C,E
Rationale: Preadministration assessment for a client with a DVT should include checking for a pedal pulse, examining the extremity for color and skin temperature, assessing for pain, and checking for a positive Homans' sign.
Which of the following may be ordered periodically during therapy with anticoagulants? Select all that apply.
- A. Urinalysis
- B. Platelet count
- C. Blood count
- D. Stool analysis
- E. Ultrasound
Correct Answer: B,C,D
Rationale: A complete blood count, platelet count, and stool analysis for occult blood may be ordered periodically throughout anticoagulant therapy.
A nurse is reviewing a journal article about antiplatelet agents. Which of the following would the nurse expect to be discussed? Select all that apply.
- A. Heparin
- B. Warfarin
- C. Abciximab
- D. Anagrelide
- E. Dipyridamole
Correct Answer: C,D,E
Rationale: Abciximab, anagrelide, and dipyridamole are antiplatelet agents. Heparin and warfarin are anticoagulants.
A client is receiving streptokinase. The nurse understands that which of the following would occur? Select all that apply.
- A. Breakdown of existing thrombi
- B. Reopening of occluded blood vessels
- C. Prevention of tissue necrosis
- D. Decreased risk of internal bleeding
- E. Prevention of formation of a thrombus
Correct Answer: A,B,C
Rationale: Streptokinase is a thrombolytic drug. Thrombolytic drugs break down existing thrombi, reopen blood vessels after occlusion, and prevent tissue necrosis.
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