A client is to receive oprelvekin (Neumega). After administering the drug, the nurse would be alert for which of the following as a possible adverse reaction? Select all that apply.
- A. Bone pain
- B. Fluid retention
- C. Syncope
- D. Nausea
- E. Fever
Correct Answer: B,C,E
Rationale: Fluid retention, peripheral edema, dyspnea, syncope, fever, and allergic reactions are adverse reactions associated with the administration of oprelvekin (Neumega).
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Based on the nurse's understanding of epoetin alfa, the nurse would expect to administer the drug cautiously to a client with a history of which of the following? Select all that apply.
- A. Diabetes
- B. Renal failure
- C. History of seizures
- D. Congestive heart failure
- E. Hypotension
Correct Answer: C,D
Rationale: Epoetin alfa (Procrit) is used cautiously in clients with hypertension, heart disease, congestive heart failure, or a history of seizures.
The nurse is preparing to administer vitamin B12 to a client. The nurse would administer the drug cautiously if the client had which condition?
- A. Pulmonary disease
- B. Hypertension
- C. Heart disease
- D. Seizures
Correct Answer: A
Rationale: Vitamin B12 is cautiously administered to clients with pulmonary disease. Epoetin alfa and darbepoetin alfa are administered cautiously to clients with hypertension, heart disease, and a history of seizures.
Prior to administering a drug used to treat anemia, the nurse should assess a client's vital signs, ability to carry out activities of daily living, and general appearance, and for the presence of which of the following other general symptoms? Select all that apply.
- A. Fatigue
- B. Pallor
- C. Headache
- D. Shortness of breath
- E. Sore tongue
Correct Answer: A,B,C,D,E
Rationale: Prior to administering a drug used to treat anemia, the nurse should assess a client's vital signs, client's ability to carry out activities of daily living, and client's general appearance, and for the presence of other general symptoms including fatigue, shortness of breath, sore tongue, headache, and pallor.
After administering methoxy polyethylene epoetin beta, the nurse would be alert for the development of which of the following as a possible adverse reaction? Select all that apply.
- A. Bone pain
- B. Fluid retention
- C. Hypertension
- D. Fatigue
- E. Arthralgia
Correct Answer: C,D,E
Rationale: Hypertension, headache, nausea, vomiting, diarrhea, rashes, fatigue, arthralgia, and injection site skin reactions are adverse reactions the nurse should discuss with a client prior to the administration of methoxy polyethylene epoetin beta (Mircera).
A nurse administers a test dose of iron dextran IM. The nurse would wait at least how long before administering the remainder of the dose?
- A. 15 minutes
- B. 30 minutes
- C. 45 minutes
- D. 60 minutes
Correct Answer: D
Rationale: After giving the test dose, the nurse would monitor the client for an allergic response for at least 1 hour after the test dose and before administering the remaining dose. Epinephrine is kept on standby in the event of severe anaphylactic reaction.
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