Roach's Introductory Clinical Pharmacology 11th Edition - Immunomodulating Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Immunomodulating Drugs related questions and content

A client with megaloblastic anemia is prescribed leucovorin. The nurse would identify which of the following as a contraindication for this drug?

  • A. Pernicious anemia
  • B. Hemochromatosis
  • C. Uncontrolled hypertension
  • D. Hypersensitivity to human albumin
Correct Answer: A

Rationale: Leucovorin is contraindicated in clients with pernicious anemia or other anemias in which vitamin B12 is deficient. Leucovorin is not contraindicated in clients with hemochromatosis, uncontrolled hypertension, and hypersensitivity to human albumin. Epoetin alfa is contraindicated in clients with uncontrolled hypertension and hypersensitivity to human albumin. Iron compounds are contraindicated in clients with hemochromatosis or hemolytic anemia.