A client receiving clomipramine is given a prescription for zolpidem for sleep. The primary health care provider was unaware the client was taking clomipramine. Which of the following reactions might the nurse observe in this client?
- A. Respiratory depression
- B. CNS depression
- C. Hypertensive crisis
- D. Easy bruising
- E. Hyperglycemia
Correct Answer: A,B
Rationale: Combining clomipramine with zolpidem increases the risk of respiratory and CNS depression due to additive sedative effects.
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Which of the following antidepressants exert their effects by inhibiting the reuptake of serotonin?
- A. Amitriptyline
- B. Bupropion
- C. Clomipramine
- D. Fluoxetine
- E. Escitalopram
Correct Answer: D,E
Rationale: Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and escitalopram specifically target serotonin reuptake, enhancing serotonin levels in the brain.
A client is prescribed phenelzine. Which of the following would the nurse instruct the client to avoid?
- A. Blue cheese
- B. Pepperoni
- C. Apples
- D. Chocolate
- E. Celery
Correct Answer: A,B,D
Rationale: Phenelzine, an MAOI, interacts with tyramine-rich foods like blue cheese, pepperoni, and chocolate, risking hypertensive crisis.
A nurse is caring for a client who has been prescribed a monoamine oxidase inhibitor (MAOI). Which of the following should the nurse instruct the client to avoid?
- A. Milk
- B. Butter
- C. Rice
- D. Yogurt
Correct Answer: D
Rationale: Yogurt contains tyramine, which can interact with MAOIs to cause hypertensive crisis; milk, butter, and rice are safe.
Which of the following would the nurse report to the primary health care provider if assessed in a client receiving an antidepressant?
- A. Weight gain
- B. Expressions of guilt
- C. Indirect threats of suicide
- D. Somnolence
- E. Insomnia
Correct Answer: B,C,E
Rationale: Expressions of guilt, indirect suicide threats, and insomnia are concerning symptoms indicating potential worsening of depression or side effects requiring medical attention.
The nurse suspects that a client is experiencing major depression based on assessment of which of the following?
- A. Feelings of hopelessness
- B. Minimal changes in weight
- C. Focused concentration
- D. Loss of energy
- E. Excessive guilt
Correct Answer: A,D,E
Rationale: Major depression is characterized by hopelessness, loss of energy, and excessive guilt, which are core diagnostic symptoms.
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