After teaching a group of nursing students about the action of antidepressants, the instructor determines that the teaching was successful when the students identify which of the following classes as exerting their effects by inhibiting reuptake of norepinephrine and serotonin?
- A. Amitriptyline
- B. Bupropion
- C. Clomipramine
- D. Duloxetine
- E. Venlafaxine
Correct Answer: A,C
Rationale: Tricyclic antidepressants like amitriptyline and clomipramine inhibit the reuptake of norepinephrine and serotonin, increasing their availability in the synaptic cleft.
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A nurse understands that the antidepressant drug paroxetine (Paxil) can be used to treat which of the following medical conditions?
- A. Enuresis
- B. Depressive episodes
- C. Anorexia
- D. Obsessive-compulsive disorders
- E. Bulimia nervosa
Correct Answer: B,D,E
Rationale: Paroxetine, an SSRI, is indicated for depressive episodes, obsessive-compulsive disorder, and bulimia nervosa due to its serotonin-modulating effects.
When assessing a client for depression, which of the following would the nurse most likely find?
- A. Drowsiness
- B. Extreme sadness
- C. Severe headache
- D. Dilated pupils
Correct Answer: B
Rationale: Extreme sadness is a hallmark symptom of depression, distinguishing it from side effects like drowsiness or symptoms of other conditions like hypertensive crisis.
Before administering an antidepressant to a client, which of the following would the nurse assess?
- A. Vital signs
- B. Presence of suicidal ideation
- C. Complete medical history
- D. Weight
- E. Mental status
Correct Answer: A,B,C,D,E
Rationale: A comprehensive assessment including vital signs, suicidal ideation, medical history, weight, and mental status is critical to ensure safe antidepressant administration.
When developing the plan of care for a client who is receiving lithium therapy, which nursing diagnosis would the nurse most likely identify as a priority?
- A. Self-Care Deficit
- B. Disturbed Sleep Pattern
- C. Imbalanced Nutrition: Less Than Body Requirements
- D. Imbalanced Fluid Volume
Correct Answer: D
Rationale: Imbalanced fluid volume is a priority due to lithium's narrow therapeutic index, where fluid status directly impacts toxicity risk.
A nurse understands that duloxetine may be used to treat which of the following?
- A. Obsessive-compulsive disorder
- B. Depression
- C. Fibromyalgia
- D. Diabetic neuropathy
- E. Stress incontinence
Correct Answer: B,C,D,E
Rationale: Duloxetine, an SNRI, is indicated for depression, fibromyalgia, diabetic neuropathy, and stress incontinence due to its effects on serotonin and norepinephrine.
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