A nurse would assess the client for an increase in anticholinergic symptoms if the client is prescribed cimetidine with which antidepressant?
- A. Phenelzine
- B. Sertraline
- C. Venlafaxine
- D. Clomipramine
- E. Escitalopram
Correct Answer: B,C,D,E
Rationale: Cimetidine can enhance anticholinergic effects of antidepressants like sertraline, venlafaxine, clomipramine, and escitalopram by inhibiting their metabolism.
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A nurse determines the need to administer a prescribed antidepressant in the morning because of the increased likelihood of insomnia. Which drug would this most likely be?
- A. Amitriptyline
- B. Bupropion
- C. Citalopram
- D. Paroxetine
- E. Sertraline
Correct Answer: C,D,E
Rationale: SSRIs like citalopram, paroxetine, and sertraline are more likely to cause insomnia, making morning administration preferable.
Which of the following antidepressants exert their effects by inhibiting the reuptake of serotonin?
- A. Amitriptyline
- B. Bupropion
- C. Clomipramine
- D. Fluoxetine
- E. Escitalopram
Correct Answer: D,E
Rationale: Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and escitalopram specifically target serotonin reuptake, enhancing serotonin levels in the brain.
A nurse understands that duloxetine may be used to treat which of the following?
- A. Obsessive-compulsive disorder
- B. Depression
- C. Fibromyalgia
- D. Diabetic neuropathy
- E. Stress incontinence
Correct Answer: B,C,D,E
Rationale: Duloxetine, an SNRI, is indicated for depression, fibromyalgia, diabetic neuropathy, and stress incontinence due to its effects on serotonin and norepinephrine.
Antidepressants can often have GI adverse reactions that can result in a nursing diagnosis of Imbalanced Nutrition: Less Than Body Requirements. Which of the following would be appropriate for the nurse to suggest to minimize these effects?
- A. Increase fiber intake
- B. Decrease fiber intake
- C. Increase fluid intake
- D. Decrease fluid intake
- E. Chew sugarless gum
Correct Answer: A,C,E
Rationale: Increasing fiber and fluid intake helps manage constipation, while sugarless gum alleviates dry mouth, both common antidepressant side effects.
A nurse is caring for a client who has been prescribed a monoamine oxidase inhibitor (MAOI). Which of the following should the nurse instruct the client to avoid?
- A. Milk
- B. Butter
- C. Rice
- D. Yogurt
Correct Answer: D
Rationale: Yogurt contains tyramine, which can interact with MAOIs to cause hypertensive crisis; milk, butter, and rice are safe.
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