Roach's Introductory Clinical Pharmacology 11th Edition - Antidepressant Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antidepressant Drugs related questions and content

A nurse is caring for a client with depression. The client has been prescribed amitriptyline. Which of the following would the nurse integrate into the teaching for the client about how the drug works?

  • A. Decreased reuptake of norepinephrine
  • B. Increased serotonin in the nervous system
  • C. Increased endogenous norepinephrine
  • D. Increased endogenous epinephrine
Correct Answer: A

Rationale: Amitriptyline, a tricyclic antidepressant, works by decreasing the reuptake of norepinephrine, increasing its availability in the synapse.