A client is receiving lithium therapy at a health care facility. The client informs the nurse that he is taking antacids for heartburn. The nurse would be alert for which of the following due to the interaction of the two drugs?
- A. Decreased effectiveness of lithium
- B. Increased risk of lithium toxicity
- C. Increased risk for bipolar disorder
- D. Increased psychotic symptoms
Correct Answer: A
Rationale: Antacids can reduce lithium absorption, leading to decreased effectiveness of the drug.
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When describing the action of antidepressants, the nursing instructor would include the belief that they exert their effect by causing slow adaptive changes to which of the following receptor systems?
- A. Beta-adrenergic
- B. Baroreceptors
- C. Norepinephrine
- D. Serotonin
- E. Nicotinic
Correct Answer: C,D
Rationale: Antidepressants, particularly those affecting monoamine systems, induce adaptive changes in norepinephrine and serotonin receptor systems, enhancing neurotransmission over time.
A nurse understands that duloxetine may be used to treat which of the following?
- A. Obsessive-compulsive disorder
- B. Depression
- C. Fibromyalgia
- D. Diabetic neuropathy
- E. Stress incontinence
Correct Answer: B,C,D,E
Rationale: Duloxetine, an SNRI, is indicated for depression, fibromyalgia, diabetic neuropathy, and stress incontinence due to its effects on serotonin and norepinephrine.
After teaching a group of nursing students about possible adverse reactions associated with trazodone, the instructor determines that the teaching was successful when the students identify which of the following?
- A. Sexual dysfunction
- B. Insomnia
- C. Priapism
- D. Diarrhea
- E. Dry mouth
Correct Answer: C,E
Rationale: Trazodone is associated with priapism and dry mouth as notable adverse reactions due to its pharmacological profile.
A client is prescribed paroxetine. When teaching the client about this drug, which of the following would the nurse include as a possible adverse reaction?
- A. Sexual dysfunction
- B. Insomnia
- C. Somnolence
- D. Diarrhea
- E. Constipation
Correct Answer: A,B,C,D,E
Rationale: Paroxetine, an SSRI, may cause a wide range of side effects including sexual dysfunction, insomnia, somnolence, diarrhea, and constipation.
A nurse is caring for an older adult client who has been prescribed amoxapine for depression accompanied by anxiety. After administration of the drug, the nurse observes muscle rigidity and sweating. The nurse identifies these as the symptoms of neuroleptic malignant syndrome. Which of the following would the nurse do next?
- A. Suggest the client engage in exercise
- B. Get the client to drink a glass of cold water
- C. Encourage the client to breathe deeply
- D. Stop the drug and contact the physician
Correct Answer: D
Rationale: Neuroleptic malignant syndrome is a medical emergency; stopping the drug and contacting the physician is the appropriate action.
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