Which of the following antidepressants exert their effects by inhibiting the reuptake of serotonin?
- A. Amitriptyline
- B. Bupropion
- C. Clomipramine
- D. Fluoxetine
- E. Escitalopram
Correct Answer: D,E
Rationale: Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and escitalopram specifically target serotonin reuptake, enhancing serotonin levels in the brain.
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When developing the plan of care for a client who is receiving lithium therapy, which nursing diagnosis would the nurse most likely identify as a priority?
- A. Self-Care Deficit
- B. Disturbed Sleep Pattern
- C. Imbalanced Nutrition: Less Than Body Requirements
- D. Imbalanced Fluid Volume
Correct Answer: D
Rationale: Imbalanced fluid volume is a priority due to lithium's narrow therapeutic index, where fluid status directly impacts toxicity risk.
After teaching a group of students about antidepressant therapy, the instructor determines that the teaching was successful when the students identify which of the following as a class of antidepressants?
- A. Selective serotonin reuptake inhibitors
- B. Tricyclics
- C. Monoamine oxidase inhibitors
- D. Benzodiazepines
- E. Barbiturates
Correct Answer: A,B,C
Rationale: SSRIs, tricyclics, and MAOIs are classes of antidepressants, while benzodiazepines and barbiturates are sedatives/hypnotics.
A nurse would assess the client for an increase in anticholinergic symptoms if the client is prescribed cimetidine with which antidepressant?
- A. Phenelzine
- B. Sertraline
- C. Venlafaxine
- D. Clomipramine
- E. Escitalopram
Correct Answer: B,C,D,E
Rationale: Cimetidine can enhance anticholinergic effects of antidepressants like sertraline, venlafaxine, clomipramine, and escitalopram by inhibiting their metabolism.
A nurse understands that the antidepressant drug paroxetine (Paxil) can be used to treat which of the following medical conditions?
- A. Enuresis
- B. Depressive episodes
- C. Anorexia
- D. Obsessive-compulsive disorders
- E. Bulimia nervosa
Correct Answer: B,D,E
Rationale: Paroxetine, an SSRI, is indicated for depressive episodes, obsessive-compulsive disorder, and bulimia nervosa due to its serotonin-modulating effects.
A nurse caring for a client taking amitriptyline for depression should monitor the client for which of the following adverse events?
- A. Sedation
- B. Diarrhea
- C. Incontinence
- D. Dry mouth
- E. Photosensitivity
Correct Answer: A,D,E
Rationale: Tricyclic antidepressants like amitriptyline commonly cause sedation, dry mouth, and photosensitivity as side effects due to their anticholinergic and antihistaminic properties.
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