Evolve HESI Medical Surgical Practice Exam Related

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A client with autosomal dominant polycystic kidney disease (ADPKD) asks, "Will my children develop this disease?" How should the nurse respond?

  • A. No genetic link is known, so your children are not at increased risk.
  • B. Your sons will develop this disease because it has a sex-linked gene.
  • C. Only if both you and your spouse are carriers of this disease.
  • D. Each of your children has a 50% risk of having ADPKD.
Correct Answer: D

Rationale: Children whose parent has the autosomal dominant form of PKD have a 50% chance of inheriting the gene that causes the disease. ADPKD is transmitted as an autosomal dominant trait and therefore is not gender-specific. Both parents do not need to have this disorder. Choice A is incorrect because ADPKD has a known genetic link and a definitive mode of inheritance. Choice B is incorrect as ADPKD is not sex-linked but autosomal dominant. Choice C is incorrect because ADPKD follows an autosomal dominant inheritance pattern and does not require both parents to be carriers for the child to inherit the disease.