A group of nursing students are reviewing information about male and female hormones. The students demonstrate understanding of the information when they identify which of the following as an anabolic steroid? Select all that apply.
- A. Nandrologe
- B. Oxyrietholone
- C. Oxandrolone
- D. Testosterone
- E. Fluoxymesterone
Correct Answer: A,B,C
Rationale: Anabolic steroids include nandrolone, oxymetholone, and oxandrolone. Testosterone and fluoxymesterone are testosterones. Note: 'Nandrologe' and 'Oxyrietholone' appear to be misspellings in the original document; the correct terms are 'nandrolone' and 'oxymetholone.'
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A nurse may be asked to administer androgen drugs to clients with which of the following medical conditions? Select all that apply.
- A. Anemia of renal insufficiency
- B. Hypogonadism
- C. Postmenopausal metastatic breast carcinoma
- D. Male-pattern baldness
- E. Benign prostatic hypertrophy
Correct Answer: B,C
Rationale: A nurse may be asked to administer androgen drugs to clients with the following medical conditions: testosterone deficiency, hypogonadism, delayed puberty, testosterone deficiency after puberty, postmenopausal metastatic breast carcinoma, and premenopausal, hormone-dependent metastatic breast carcinoma.
A female client receiving fluoxymesterone for metastatic breast cancer is disturbed by the physical changes seen in her body. The nurse provides support to the client based on assessment of which of the following features the client is experiencing related to this therapy?
- A. Deepening of the voice
- B. Hypopigmentation of the skin
- C. Decrease in clitoris size
- D. Increase in body weight
Correct Answer: A
Rationale: Deepening of the voice may be seen as a feature of virilization following male hormone therapy in a female client. Virilization is the acquisition of male characteristics in the female. Other features of virilization include pigmentation, and not hypopigmentation, of the skin and an increase, not a decrease, in the size of the clitoris. An increase in body weight is not a sign of virilization. It may occur due to impaired nutrition of the body.
A nurse is teaching a client about transdermal estrogen therapy. The nurse understands that this method of delivery has been found to be safer especially for women with which of the following conditions? Select all that apply.
- A. Hypertriglyceridemia
- B. Type 2 diabetes
- C. Migraine headaches
- D. Hypertension
- E. Rheumatoid arthritis
Correct Answer: A,B,C,D
Rationale: Transdermal delivery of estrogens has been found to be safer especially for women with hypertriglyceridemia, type 2 diabetes, hypertension, and migraine headaches and those who smoke.
A female client with inoperable advanced breast cancer is prescribed methyltestosterone. The nurse would be alert for the development of which of the following? Select all that apply.
- A. Amenorrhea
- B. Acne
- C. Facial hair growth
- D. Somnolence
- E. Mania
Correct Answer: A,B,C
Rationale: A nurse should advise a female client beginning therapy with methyltestosterone (Testred) for the treatment of inoperable advanced breast carcinoma of the following adverse reactions: amenorrhea, other menstrual irregularities, acne, male-pattern baldness, and virilization (facial hair growth, voice deepening, and clitoromegaly).
A nurse is caring for a client with advanced breast cancer who is receiving androgen therapy. Which of the following signs might alert the nurse to the possibility of liver toxicity?
- A. Edema of the feet
- B. Increase in appetite
- C. Clinical jaundice
- D. Increase in weight
Correct Answer: C
Rationale: Liver toxicity is indicated by the presence of jaundice. Edema of the feet and an increase in weight may be seen because of fluid and electrolyte imbalance but does not indicate liver toxicity. An increase in appetite shows that the client is responding well to the drug and is not a sign of liver toxicity.
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