Nokea
A group of nursing students are reviewing NSAIDs. The students demonstrate understanding of this drug class when they identify which of the following as an NSAID? Select all that apply.
- A. Eletriptan (Relpax)
- B. Aspirin (Ecotrin)
- C. Meloxicam (Mobic)
- D. Acetaminophen (Tylenol)
- E. Ibuprofen (Motrin)
Correct Answer: C,E
Rationale: Ibuprofen and meloxicam are both classified as NSAIDs. Aspirin is a salicylate, acetaminophen is a nonsalicylate, and eletriptan is a serotonin receptor agonist.
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A nurse is describing the actions of NSAIDs to a client. Which of the following would the nurse integrate into the description as a mechanism by which NSAIDs elicit their effects? Select all that apply.
- A. Inhibition of prostaglandins
- B. Inhibition of cyclooxygenase-1
- C. Synthesis of cyclooxygenase-2
- D. Synthesis of cyclooxygenase-3
- E. Inhibition of platelet aggregation
Correct Answer: A,B,C
Rationale: NSAIDs exert their effects by inhibition of prostaglandin synthesis via inhibition of cyclooxygenase-1 and -2.
A 60-year-old client with rheumatoid arthritis visits the health care facility for a regular checkup. The client informs the nurse that he has been using an over-the-counter NSAID for the last few days. The nurse cautions the client about the use of NSAIDs on a long-term basis because of the increased risk for which of the following?
- A. Ulcer disease
- B. CNS disorders
- C. Hearing impairment
- D. Blindness
Correct Answer: A
Rationale: Age appears to increase the possibility of adverse reactions to NSAIDs. The risk of serious ulcer disease in adults older than 65 years is increased with higher doses of NSAIDs. CNS disorders, hearing impairment, and blindness are not effects associated with using NSAIDs on a long-term basis in older clients.
Prior to administering an NSAID to a client, the nurse should obtain which of the following? Select all that apply.
- A. History of allergies
- B. Pain assessment
- C. Current medical conditions
- D. Past medical conditions
- E. Vital signs
Correct Answer: A,B,C,D,E
Rationale: Before administering an NSAID, the nurse should obtain a history of allergies and past medical conditions. Other preadministration assessment includes pain, current medical conditions and vital signs.
A nursing instructor is preparing a class discussion on the use of NSAIDs and interactions with other drugs. The instructor would emphasize that the effects of which of the following can increase with NSAID therapy? Select all that apply.
- A. Lithium
- B. Cyclosporine
- C. Furosemide
- D. Lisinopril
- E. Phenytoin
Correct Answer: A,B,E
Rationale: The use of NSAIDs can increase the effectiveness of lithium, cyclosporine, and phenytoin, possibly leading to toxicity.
A nurse is caring for a client who is required to take NSAIDS on an outpatient basis. Which of the following would the nurse include in the teaching plan for the client and family?
- A. Take aspirin if necessary strictly with a full glass of water.
- B. Use the drug on a very regular basis during treatment.
- C. Call your primary care provider if you have no relief after 2 weeks.
- D. Take the drugs strictly with a glass of milk or juice.
Correct Answer: C
Rationale: The nurse should instruct the patient to consult the primary health care provider if the pain, swelling, inflammation, or tendemess is not relieved after 2 weeks. The drug takes several days to relieve the discomfort, so it is important for the patient to give the drug time to work. The nurse should instruct the patient to avoid the use of aspirin. The drug should be taken with a full glass of water or with food. It is not necessary to take NSAIDs strictly with a glass of juice or milk. These drugs are not to be used on a regular basis unless the patient is strictly instructed to do so by the primary health care provider.