LPN Pharmacology Practice Questions

LPN Pharmacology Practice Questions Related

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A healthcare professional is preparing to administer ceftriaxone 1 g IM to a client who has a pelvic infection. Which of the following actions should the healthcare professional plan to take?

  • A. Administer the medication via IM bolus over 5 minutes.
  • B. Reconstitute with 0.9% sodium chloride.
  • C. Discard the reconstituted medication if it is cloudy.
  • D. Administer the medication in a large muscle.
Correct Answer: D

Rationale: Administering ceftriaxone in a large muscle is crucial for proper absorption and to reduce the risk of pain or tissue irritation. Intramuscular administration of ceftriaxone helps achieve optimal therapeutic levels in the bloodstream for the treatment of the pelvic infection. Choices A, B, and C are incorrect. Choice A is not recommended as ceftriaxone should not be administered as a bolus over 5 minutes. Choice B is irrelevant because the question is about the administration route, not the reconstitution process. Choice C is also irrelevant as it does not pertain to the administration but to the quality of the reconstituted medication.

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While assessing a client taking propranolol, which finding should the nurse report to the provider?

  • A. Bradycardia
  • B. Dry mouth
  • C. Constipation
  • D. Increased appetite
Correct Answer: A

Rationale: Bradycardia is a significant side effect of propranolol, a beta-blocker that slows the heart rate. It indicates potential cardiovascular complications and should be reported promptly to the healthcare provider for further evaluation and management. Dry mouth, constipation, and increased appetite are common side effects of various medications but are not directly associated with propranolol's mechanism of action.

Nurse practitioner prescriptive authority is regulated by:

  • A. The National Council of State Boards of Nursing
  • B. The U.S. Drug Enforcement Administration
  • C. The State Board of Nursing for each state
  • D. The State Board of Pharmacy
Correct Answer: C

Rationale: The correct answer is choice C, the State Board of Nursing for each state, because these boards establish the legal scope of practice for nurse practitioners, including prescriptive authority, which varies by state due to differing regulations. Choice A, the National Council of State Boards of Nursing, is incorrect as it provides guidelines and licensure standards but doesn't directly regulate state-specific authority. Choice B, the U.S. Drug Enforcement Administration, is wrong because it oversees controlled substances, not general prescribing rights. Choice D, the State Board of Pharmacy, is also incorrect since it governs pharmacists, not NPs, and has no jurisdiction over their prescriptive authority.

Drugs that should be avoided in transgender men receiving testosterone therapy include:

  • A. Estrogen
  • B. Alpha blockers
  • C. Beta blockers
  • D. All of the above
Correct Answer: A

Rationale: Choice A is correct because estrogen counteracts testosterone's masculinizing effects in transgender men, conflicting with therapy aims, so it's avoided. Choice B is incorrect as alpha blockers don't interfere with testosterone goals. Choice C is wrong because beta blockers are unrelated to therapy effects. Choice D is incorrect since only estrogen applies.

Pharmacokinetic changes in women's bodies that affect drug dosing include:

  • A. Increased body fat
  • B. Increased glomerular filtration rate in pregnancy
  • C. Decreased gastric emptying
  • D. All of the above
Correct Answer: D

Rationale: Choice D is correct because increased body fat (alters distribution), higher GFR in pregnancy (increases clearance), and slower gastric emptying (affects absorption) all change pharmacokinetics, impacting dosing. Choice A is incorrect alone as fat is one change. Choice B is wrong by itself because GFR is just part. Choice C is incorrect solo since gastric emptying is only one factor.

Men may require higher doses of which drug class due to differences in body composition?

  • A. Lipid-soluble drugs
  • B. Water-soluble drugs
  • C. Drugs that are highly protein bound
  • D. All of the above
Correct Answer: B

Rationale: Choice B is correct because men's greater lean mass dilutes water-soluble drugs, often requiring higher doses for efficacy, unlike others. Choice A is incorrect as lipid-soluble drugs align with fat, lower in men. Choice C is wrong because protein binding isn't sex-specific here. Choice D is incorrect since only water-soluble drugs apply.

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