Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017) - Assessment and Management of Patients With Male Reproductive Disorders Related

Review Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017) - Assessment and Management of Patients With Male Reproductive Disorders related questions and content

A man tells the nurse that his father died of prostate cancer and he is concerned about his own risk of developing the disease, having heard that prostate cancer has a genetic link. What aspect of the pathophysiology of prostate cancer would underlie the nurses response?

  • A. A number of studies have identified an association of BRCA-2 mutation with an increased risk of prostate cancer.
  • B. HNPCC is a mutation of two genes that causes prostate cancer in men and it is autosomal dominant.
  • C. Studies have shown that the presence of the TP53 gene strongly influences the incidence of prostate cancer.
  • D. Recent research has demonstrated that prostate cancer is the result of lifestyle factors and that genetics are unrelated.
Correct Answer: A

Rationale: BRCA-2 mutations are associated with an increased risk of prostate cancer, particularly in men with a family history. HNPCC relates to colon cancer, TP53 is linked to breast cancer, and genetics, not just lifestyle, contribute to prostate cancer risk.