A nurse caring for a client taking warfarin (Coumadin) develops a UTI. The nurse should monitor the client for increased risk of bleeding if which of the following anti-infectives is prescribed?
- A. Amoxicillin
- B. Methenamine
- C. Sulfamethoxazole
- D. Nitrofurantoin
Correct Answer: C
Rationale: Sulfamethoxazole, when administered concomitantly with warfarin (Coumadin), can increase a client's risk for bleeding. This interaction is not associated with amoxicillin, methenamine, or nitrofurantoin.
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A nurse caring for a client being treated with nitrofurantoin (Macrodantin) for a UTI should ask the client specifically about resolution of which of the following symptoms during ongoing assessment? Select all that apply.
- A. Urgency
- B. Frequency
- C. Pressure
- D. Burning during urination
- E. Pain during urination
Correct Answer: A,B,C,D,E
Rationale: Clinical manifestations of a UTI include urgency, frequency, pressure, burning and pain on urination, and pain caused by spasm in the region of the bladder and the suprapubic area and should be assessed by the nurse during ongoing assessment to determine effectiveness of drug therapy.
A nurse is caring for a client receiving amoxicillin for the treatment of an acute bacterial urinary tract infection. After administering the drug, the nurse would be alert for which of the following as an adverse reaction to the drug?
- A. Abdominal cramps
- B. Vaginitis
- C. Bladder irritation
- D. Stomatitis
Correct Answer: D
Rationale: The nurse should monitor for stomatitis in the client, which is an adverse reaction to amoxicillin, an anti-infective drug. Vaginitis is an adverse reaction to an anti-infective drug called fosfomycin. Abdominal cramps and bladder irritation are adverse reactions to the anti-infective drug methenamine.
A nurse is educating a client receiving sulfamethoxazole/trimethoprim (Septra) about common dermatologic adverse reactions. Which of the following would the nurse include in the teaching? Select all that apply.
- A. Rash
- B. Stevens-Johnson syndrome
- C. Photosensitivity
- D. Exfoliative dermatitis
- E. Pruritus
Correct Answer: A,C,E
Rationale: Common dermatologic adverse reactions seen with the use of sulfamethoxazole/trimethoprim (Septra) include rash, photosensitivity, pruritus, and urticaria.
A nurse caring for a client taking which of the following drugs may notice increased adverse reactions if the client was prescribed nitrofurantoin (Macrodantin) resulting from an increased absorption of nitrofurantoin (Macrodantin)? Select all that apply.
- A. Benztropine (Cogentin)
- B. Simvastatin (Zocor)
- C. Tiotropium (Spiriva)
- D. Albuterol (Proventil)
- E. Dicyclomine (Bentyl)
Correct Answer: A,C,E
Rationale: Anticholinergic drugs, like benztropine (Cogentin), tiotropium (Spiriva), and dicyclomine (Bentyl), can cause delayed gastric emptying, leading to increased absorption of nitrofurantoin (Macrodantin), which may result in increased adverse reactions.
A nurse monitoring a hospitalized client with a UTI notifies the physician if which of the following occur with drug therapy? Select all that apply.
- A. Fever
- B. Poor fluid intake
- C. Decreased urinary output
- D. Appearance of concentrated urine
- E. Worsening of UTI symptoms
Correct Answer: A,B,C,D,E
Rationale: A nurse monitoring a hospitalized client with a UTI notifies the physician if any of the following occur: fever, poor fluid intake, decreased urinary output, appearance of concentrated urine, or worsening of UTI symptoms.
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