Roach's Introductory Clinical Pharmacology 11th Edition - Cardiotonic and Inotropic Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Cardiotonic and Inotropic Drugs related questions and content

A nurse checks the serum digoxin level of a client and finds it to be increased. Which of the following would the nurse identify as possibly associated with this increase?

  • A. Colestipol (Colestid)
  • B. Verapamil (Calan)
  • C. Clarithromycin (Biaxin)
  • D. Calcium carbonate (Maalox)
  • E. Spironolactone (Aldactone)
Correct Answer: B,C,E

Rationale: Increased serum digoxin levels can occur with verapamil, clarithromycin, and spironolactone. Antacids, such as calcium carbonate, and colestipol cause a decrease in serum digoxin levels.