Roach's Introductory Clinical Pharmacology 11th Edition - Cardiotonic and Inotropic Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Cardiotonic and Inotropic Drugs related questions and content

Which of the following is true with regard to oral administration of cardiotonic drugs? Select all that apply.

  • A. Capsule doses are less absorbed.
  • B. Alternating between oral dosage forms is avoided.
  • C. Tablets can be crushed and mixed with food or fluids.
  • D. Oral dosage forms can be administered without regard to meals.
  • E. The recommended dosage of the capsules is 80% more than that of tablets.
Correct Answer: B,C,D

Rationale: Oral preparations can be given without regard to meals. Tablets can be crushed and mixed with food or fluids if the patient has difficulty swallowing. Do not alternate between the dosage forms (i.e., tablets and capsules); these dosages are not the same. Owing to better absorption, the recommended dosage of the capsules is 80% of the dosage for tablets and elixir.