A nurse determines that an opioid antagonist would most likely be needed in which situation?
- A. Postoperative acute respiratory depression
- B. Reversal of phenytoin toxicity
- C. Reversal of opioid-induced hypotension
- D. Suspected acute benzodiazepine overdosage
- E. Suspected acute opioid overdosage
Correct Answer: A,C,E
Rationale: Opioid antagonists are used for the treatment of the following: postoperative acute respiratory depression, reversal of opioid adverse effects (hypotension, bradycardia, etc.), and suspected acute opioid overdosage.
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A client is receiving an opioid antagonist. The nurse would closely monitor the client for which of the following?
- A. Cramps
- B. Sweating
- C. Low blood pressure
- D. Skin inflammation
Correct Answer: B
Rationale: The nurse should monitor for sweating when caring for the client since it is one of the adverse reactions of opioid antagonists. Other adverse reactions include nausea, vomiting, tachycardia, increased blood pressure, and tremors. The nurse need not monitor for cramps, low blood pressure, or skin inflammation since these conditions are not known to be caused by opioid antagonists.
Which of the following can occur if the nurse administers naloxone (Narcan) as a rapid IV bolus?
- A. Withdrawal
- B. Intense pain
- C. Vomiting
- D. Hypotension
- E. Respiratory depression
Correct Answer: A,B,C
Rationale: Withdrawal, return of intense pain, and vomiting may occur if the nurse administers naloxone (Narcan) as a rapid IV bolus.
After administering an opioid antagonist, which of the following would be most appropriate for the nurse to do when the client's pain recurs?
- A. Change opioid antagonists.
- B. Review the circumstances that led to the use of the opioid antagonist.
- C. Assess the client's pain level.
- D. Begin to treat the pain again.
- E. Decrease the rate of opioid antagonist administration.
Correct Answer: B,C,D
Rationale: The nurse should assess the client's pain level, review the circumstances that required the use of the antagonist, and begin to treat the pain again. Changing antagonists and decreasing the rate of antagonist administration are inappropriate.
After teaching a group of nursing students about opioid antagonists, the instructor determines that the teaching was successful when the students identify which of the following as an example?
- A. Naproxen
- B. Nalbuphine
- C. Naloxone
- D. Nevirapine
Correct Answer: C
Rationale: Naloxone is an opioid antagonist. Naproxen is an NSAID. Nalbuphine is an opioid agonist-antagonist. Nevirapine is an antiretroviral agent.
Which of the following are evaluations the nurse should make when caring for a client receiving naloxone?
- A. Pain relief is resumed.
- B. Adverse reactions are identified and managed.
- C. Therapeutic response is achieved.
- D. Client demonstrates an understanding of the drug regimen.
- E. Client's respiratory rate is normal.
Correct Answer: A,B,C,D,E
Rationale: Pain relief is resumed, adverse reactions are identified and managed, therapeutic response is achieved, client demonstrates an understanding of the drug regimen, and client's respiratory rate is normal are evaluations of successful therapy with an opioid antagonist.
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