A nurse has administered drugs to a patient as per the physician's orders. Which of the following activities should the nurse perform after administering the prescribed drugs to the patient?
- A. Record symptoms of the condition.
- B. Perform a culture and sensitivity test.
- C. Obtain history of drug allergy.
- D. Check for adverse drug reactions.
Correct Answer: D
Rationale: After administering the drug to the patient, the nurse should observe the patient for adverse drug reactions. Recording symptoms of infection, performing a culture and sensitivity test, and obtaining a history of drug allergy are typically performed by the nurse in the preadministration assessment stage.
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A drug may be classified by which of the following? Select all that apply.
- A. The chemical type of the drug's active ingredient
- B. The way the drug is used to treat a specific condition
- C. The generic name of the drug
- D. The trade name of the drug
- E. The nonproprietary name of the drug
Correct Answer: A,B
Rationale: A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Generic, trade, and nonproprietary refer to how a drug is named.
A nurse is assessing a client and notes that the client has developed swelling of the eyelids and lips after administration of a prescribed medication. The nurse interprets this finding as specifically indicating which of the following?
- A. Mild allergic reaction
- B. Anaphylactic shock
- C. Angioedema
- D. Drug idiosyncrasy
Correct Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of fluid in the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and throat. Allergic reactions can be manifested by a wide range of signs and symptoms such as itching, rashes, and hives. Anaphylactic shock is a serious allergic reaction that requires immediate medical attention. Drug idiosyncrasy describes any unusual or abnormal reaction to a drug, one that is different from the one normally expected.
After teaching a group of nursing students about the half-life of a drug, the instructor determines the need for additional teaching when the students identify which of the following as true? Select all that apply.
- A. Half-life can be decreased in clients with renal disease.
- B. Half-life can help determine dosing frequency.
- C. Half-life does not change throughout a client's life.
- D. Layer disease can increase half-life.
- E. Half-life is the measure of the rate at which drugs are removed from the body.
Correct Answer: A,C
Rationale: Half-life is the measure of the rate at which drugs are removed from the body, and any difficulty in excreting a drug increases half-life, including liver or kidney disease or advanced age.
When reviewing the phases of drug development, the nurse finds a discussion about the postmarketing surveillance phase. Which one of the following activities would the nurse expect to find as being carried out during this phase?
- A. Health care providers report adverse effects to FDA.
- B. Healthy volunteers are involved in the test.
- C. In vitro tests are performed using human cells.
- D. The drug is given to patients with the disease.
Correct Answer: A
Rationale: The postmarketing surveillance phase of drug development encourages health care professionals to report adverse effects of drugs to the FDA using MedWatch. Phase 1 of clinical testing involves 20 to 100 healthy volunteers. In vitro testing of the drug on human or animal cells is done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is given to patients with the disease for which the drug is manufactured.
A nurse is assessing a client after administering a prescribed medication. Which of the following would alert the nurse to suspect that the client is developing anaphylactic shock? Select all that apply.
- A. Bradycardia
- B. Hypertension
- C. Dyspnea
- D. Urticaria
- E. Angioedema
Correct Answer: C,D,E
Rationale: The symptoms of anaphylactic shock are dyspnea, feeling of fullness in the throat, cough, wheezing, extremely low blood pressure, tachycardia (heart rate =100 bpm), palpitations, syncope, cardiac arrest, urticaria, angioedema, pruritus, sweating, nausea, vomiting, and abdominal pain.
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