A nurse has admitted a patient who has been diagnosed with urosepsis. What immune response predominates in sepsis?
- A. Mitigated
- B. Nonspecific
- C. Cellular
- D. Humoral
Correct Answer: D
Rationale: Most immune responses to antigens involve both humoral and cellular responses, although only one predominates. For example, during transplantation rejection, the cellular response predominates, whereas in the bacterial pneumonias and sepsis, the humoral response plays the dominant role. Neither mitigated nor nonspecific cell response is noted in this situation.
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A nurse is explaining how the humoral and cellular immune responses should be seen as interacting parts of the broader immune system rather than as independent and unrelated processes. What aspect of immune function best demonstrates this?
- A. The movement of B cells in and out of lymph nodes
- B. The interactions that occur between T cells and B cells
- C. The differentiation between different types of T cells
- D. The universal role of the complement system
Correct Answer: B
Rationale: T cells interact closely with B cells, indicating that humoral and cellular immune responses are not separate, unrelated processes, but rather branches of the immune response that interact. Movement of B cells does not clearly show the presence of a unified immune system. The differentiation between types of T cells and the role of the complement system do not directly suggest a single immune system.
A patient has undergone treatment for septic shock and received high doses of numerous antibiotics during the course of treatment. When planning the patients subsequent care, the nurse should be aware of what potential effect on the patients immune function?
- A. Bone marrow suppression
- B. Uncontrolled apoptosis
- C. Thymus atrophy
- D. Lymphoma
Correct Answer: A
Rationale: Large doses of antibiotics can precipitate bone marrow suppression, affecting immune function. Antibiotics are not noted to cause apoptosis, thymus atrophy, or lymphoma.
The nurse knows that the response of natural immunity is enhanced by processes that are inherent in the physical and chemical barriers of the body. What is a chemical barrier that enhances the response of natural immunity?
- A. Cell cytoplasm
- B. Interstitial fluid
- C. Gastric secretions
- D. Cerebrospinal fluid
Correct Answer: C
Rationale: Chemical barriers, such as mucus, acidic gastric secretions, enzymes in tears and saliva, and substances in sebaceous and sweat secretions, act in a nonspecific way to destroy invading bacteria and fungi. Not all body fluids are chemical barriers, however. Cell cytoplasm, interstitial fluid, and CSF are not normally categorized as chemical barriers to infection.
A nurse has administered a childs scheduled vaccination for rubella. This vaccination will cause the child to develop which of the following?
- A. Natural immunity
- B. Active acquired immunity
- C. Cellular immunity
- D. Mild hypersensitivity
Correct Answer: B
Rationale: Active acquired immunity usually develops as a result of vaccination or contracting a disease. Natural immunity is present at birth and provides a nonspecific response to any foreign invader. Immunizations do not activate the process of cellular immunity. Hypersensitivity is not an expected outcome of immunization.
A gardener sustained a deep laceration while working and requires sutures. The patient is asked about the date of her last tetanus shot, which is over 10 years ago. Based on this information, the patient will receive a tetanus immunization. The tetanus injection will allow for the release of what?
- A. Antibodies
- B. Antigens
- C. Cytokines
- D. Phagocytes
Correct Answer: A
Rationale: Immunizations activate the humoral immune response, culminating in antibody production. Antigens are the substances that induce the production of antibodies. Immunizations do not prompt cytokine or phagocyte production.
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