A nurse in the operating room is caring for a client who received a dose of Succinylcholine. During the operation, the client suddenly develops rigidity, and his body temperature begins to rise. The nurse should anticipate a prescription for which of the following medications?
- A. Neostigmine
- B. Naloxone
- C. Dantrolene
- D. Vecuronium
Correct Answer: C
Rationale: Dantrolene treats malignant hyperthermia, characterized by rigidity and hyperthermia.
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Insulin medications are not administered per os because
- A. Are poorly absorbed in GI truct
- B. They are breaksdown by the action of dygestive enzymes
- C. Increase glucose absorbtion
Correct Answer: B
Rationale: Insulin is a peptide broken down by digestive enzymes, rendering oral administration ineffective.
When a pharmacoeconomic analysis looks at two or more treatment alternatives that are considered equal in efficacy and compares the costs of each it is referred to as:
- A. Cost-minimization analysis
- B. Cost-of-illness analysis
- C. Cost-effectiveness analysis
- D. Cost-benefit analysis
Correct Answer: A
Rationale: Cost-minimization analysis compares costs of equally effective treatments.
Which example best demonstrates safe drug administration by the nurse?
- A. Administering an oral medication with the patient sitting upright
- B. Asking children to say their name before administering the medication
- C. Leaving the medications on the bedside stand after verifying patient identification
- D. Returning the unused portion of a medication to a stock supply bottle
Correct Answer: A
Rationale: Sitting the patient upright for oral medications is safe medication practice. Children should never be asked their names as a means of positive identification. Remaining with a patient until the drug is swallowed is safe practice. Returning an unused portion of medication to the stock supply bottle is not safe medication practice.
A client who has been newly diagnosed with diabetes mellitus has been stabilized with daily insulin injections. Which information should the nurse teach when carrying out plans for discharge?
- A. Keep insulin vials refrigerated at all times.
- B. Rotate the insulin injections systematically.
- C. Increase the amount of insulin before unusual exercise.
- D. Monitor the urine acetone level to determine the insulin dosage.
Correct Answer: B
Rationale: Insulin dosages should not be adjusted or increased before unusual exercise. If acetone is found in the urine, it may possibly indicate the need for additional insulin. To minimize the discomfort associated with insulin injections, the insulin should be administered at room temperature. Injection sites should be systematically rotated from one area to another. The client should be instructed to give injections in one area, about 1 inch apart, until the whole area has been used and then to change to another site. This prevents dramatic changes in daily insulin absorption.
Tick the second messenger of G-protein-coupled (metabotropic) receptor:
- A. Adenylyl cyclase
- B. Sodium ions
- C. Phospholipase C
- D. cAMP
Correct Answer: D
Rationale: cAMP is a classic second messenger generated by G-protein-coupled receptors via adenylyl cyclase.