Nokea
Piroxicam has a particularly long half-life (50 hours) as it undergoes enterohepatic recycling.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Piroxicam's long half-life is due to enterohepatic recycling, prolonging its presence in the body.
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A 27-year-old male is admitted to the Emergency Department (ED) after a serious motorcycle accident. The patient has a head injury, abrasions covering the left side of his body, a broken left femur, and internal injuries that are not fully assessed at this time. He is transferred from the ED to the ICU. The nurse who is going to care for this patient in the ICU knows that one of their most important responsibilities in regard to drug therapy is what?
- A. Support vital functions
- B. Continue curative treatment
- C. Institute life-saving treatment
- D. Monitor the patient's response
Correct Answer: D
Rationale: Monitoring drug response ensures timely adjustments in critical care, optimizing therapy amidst multiple injuries.
A nurse is caring for a client who has a new prescription for Lithium Carbonate. When teaching the client about ways to prevent Lithium toxicity, the nurse should advise the client to do which of the following?
- A. Avoid the use of acetaminophen for headaches.
- B. Restrict intake of foods rich in sodium.
- C. Decrease fluid intake to less than 1,500 mL daily
- D. Limit aerobic activity in hot weather
Correct Answer: D
Rationale: Limiting activity in hot weather prevents dehydration, which increases lithium levels and risk of toxicity.
Midazolam as compared to diazepam is:
- A. Less cerebroprotective
- B. More cerebroprotective
- C. Same as diazepam
- D. No cerebroprotective effect
Correct Answer: A
Rationale: Midazolam is less cerebroprotective than diazepam.
Which of the following patients would be at higher risk of experiencing adverse drug reactions (ADRs):
- A. A 32-year-old male
- B. A 22-year-old female
- C. A 3-month-old female
- D. A 48-year-old male
Correct Answer: C
Rationale: Infants like a 3-month-old have immature organ systems, increasing ADR risk compared to healthy adults.
Administration of sulfonamide may intensify the action of tolbutamide, through:
- A. Activation of the islets of pancreas
- B. Direct action on the utilization of glucose
- C. Synergistic action
- D. Competing with tolbutamide in plasma protein binding
Correct Answer: D
Rationale: Sulfonamides displace tolbutamide from plasma proteins, increasing free drug levels and enhancing its hypoglycemic effect.