Nokea
Tick the second messenger of G-protein-coupled (metabotropic) receptor:
- A. Adenylyl cyclase
- B. Sodium ions
- C. Phospholipase C
- D. cAMP
Correct Answer: D
Rationale: cAMP is a classic second messenger generated by G-protein-coupled receptors via adenylyl cyclase.
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Which hormones are produces by pancreas?
- A. Calcitirne
- B. Corticotropin
- C. Insuline
- D. Dopamine
Correct Answer: C
Rationale: Insulin and glucagon are produced by the pancreas, regulating blood glucose levels; the others are not pancreatic hormones.
A patient is considering using herbal supplements and asks the nurse about them. Which response by the nurse would be most appropriate?
- A. Herbal supplements are safe to use because they are regulated closely.'
- B. Herbal supplements can affect the way other medications will act.'
- C. Taking more than the recommended amount usually is not harmful because they are natural.'
- D. The risk of the supplement interacting with any prescription medications is extremely low.'
Correct Answer: B
Rationale: The nurse needs to explain to the patient that just because an herbal supplement is labeled 'natural' does not mean the supplement is safe or without harmful effects. Herbal supplements can act the same way as drugs and can cause medical problems if not used correctly or if taken in large amounts. Herbal supplements are not regulated by the FDA, so products lack standardization in relation to purity and potency. In addition, the patient should be warned not to take more than the recommended dose of any herbal health product or supplement. The problems that these products can cause are much more likely to occur if the patient takes too much or takes them for too long.
What is the fraction of unchanged drug reaching the systemic circulation?
- A. Elimination
- B. Bioavailability
- C. Metabolism
- D. Drug displacement
Correct Answer: B
Rationale: Bioavailability is defined as the fraction of unchanged drug that reaches systemic circulation, a key pharmacokinetic parameter.
Which of the following is not an indication that growth hormone supplements should be discontinued?
- A. Imaging indication of epiphyseal closure
- B. Growth curve increases have plateaued
- C. Complaints of mild bone pain
- D. Achievement of anticipated height goals
Correct Answer: C
Rationale: Mild bone pain is a common side effect of growth hormone, not a stop signal; closure or plateau are.
Harold, a 42-year-old African American, has moderate persistent asthma. Which of the following asthma medications should be used cautiously, if at all?
- A. Betamethasone, an inhaled corticosteroid
- B. Salmeterol, an inhaled long-acting beta-agonist
- C. Albuterol, a short-acting beta-agonist
- D. Montelukast, a leukotriene modifier
Correct Answer: B
Rationale: Salmeterol carries a Black Box Warning for increased asthma-related deaths, especially in African Americans, requiring caution; others are safer.