Nokea
A nurse is administering digoxin to a patient. To administer medications so that the drug is as effective as possible, the nurse needs to consider what?
- A. Peak plasma level
- B. Half-life
- C. Drug interactions
- D. Timing of administration
Correct Answer: D
Rationale: To maximize digoxin's effectiveness, the nurse must consider timing of administration to align with therapeutic levels and avoid toxicity, especially given its narrow therapeutic index. Peak plasma level, half-life, and drug interactions are factors, but timing is critical for efficacy.
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You need to infuse 1,200 mL of a medication over 6 hours with a drop factor of 10 gtt/mL. Calculate the flow rate in drops per minute.
- A. 30 gtt/min
- B. 33 gtt/min
- C. 40 gtt/min
- D. 50 gtt/min
Correct Answer: B
Rationale: Flow rate = (1,200 mL 10 gtt/mL) ÷ (6 60) = 12,000 ÷ 360 = 33.33 gtt/min, rounded to 33 gtt/min (same as Q4).
A nurse is planning to administer subcutaneous enoxaparin 40 mg using a prefilled syringe of Enoxaparin 40 mg/0.4 mL to an adult client following hip arthroplasty. Which of the following actions should the nurse plan to take?
- A. Expel the air bubble from the prefilled syringe before injecting.
- B. Insert the needle completely into the client's tissue.
- C. Administer the injection in the client's thigh.
- D. Aspirate carefully after inserting the needle into the client's skin
Correct Answer: B
Rationale: Inserting the needle fully ensures proper subcutaneous delivery; air bubbles are not expelled in prefilled syringes.
Phase IV clinical trials in the United States are also known as:
- A. Human bioavailability trials
- B. Post marketing research
- C. Human safety and efficacy studies
- D. The last stage of animal trials before the human trials begin
Correct Answer: B
Rationale: Phase IV is post-marketing research , monitoring drugs after approval, unlike earlier phases or animal studies.
When assessing a patient before starting a drug regimen, why would the nurse consider it important to assess baseline kidney function?
- A. To anticipate adverse effects of drugs
- B. To determine patient's baseline electrolyte levels
- C. To determine patient's ability to excrete the drug
- D. To determine patient's ability to metabolize the drug
Correct Answer: C
Rationale: Kidney function determines drug excretion, critical for dosing and avoiding toxicity.
Patient education when prescribing clopidogrel includes:
- A. Do not take any herbal products without discussing it with the provider
- B. Monitor urine output closely and contact the provider if it decreases
- C. Clopidogrel can be constipating, use a stool softener if needed
- D. The patient will need regular anticoagulant studies while on clopidogrel
Correct Answer: A
Rationale: Herbal products can increase bleeding risk with clopidogrel; urine or constipation aren't typical issues, and INR isn't monitored.