Nokea
A nurse is caring for a client who is receiving daily doses of Oprelvekin. Which of the following laboratory values should the nurse monitor to determine effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood count
Correct Answer: C
Rationale: Oprelvekin increases platelet count , its primary therapeutic effect.
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Which of the following is a disadvantage of using oral drugs
- A. First pass effect
- B. Low bioavailability
- C. Overdose overcome by antidotes
- D. A and B
Correct Answer: D
Rationale: Oral drugs face the first-pass effect and often have lower bioavailability due to liver metabolism, making D (A and B) the correct combined disadvantage.
The patient tells the nurse about a new drug being tested to treat the disease she was diagnosed with and asks the nurse whether the doctor can prescribe a medication still in the preclinical phase of testing. What is the nurse's best response?
- A. The doctor would have to complete a great deal of paperwork to get approval to prescribe that drug.
- B. Sometimes pharmaceutical companies are looking for volunteers to test a new drug and the doctor could give them your name.
- C. Drugs in the preclinical phase of testing are only tested on animals and so would not be available to you.
- D. Drugs in the preclinical phase of testing are given only to healthy young men and so would not be available to you.
Correct Answer: C
Rationale: During the preclinical phase of testing drugs are tested on animals and are not available to patients. In phase I, the drug is tested on volunteers who are usually healthy young men. It is only in phase III studies that the drug is made available to prescribers who agree to closely monitor patients getting the medication.
A patient taking an oral diuretic for about six (6) months presents with elevated fasting and post prandial blood glucose levels. You suspect the glycemic problems are diuretic induced. What is the most likely cause?
- A. Acetazolamide
- B. Amiloride
- C. Chlorothiazide
- D. Spironolactone
Correct Answer: C
Rationale: Thiazides like chlorothiazide impair glucose tolerance by reducing insulin sensitivity.
Which statement is correct regarding glucagon:
- A. Causes hypoglicemia
- B. Causes hyperglicemia
- C. Haven't affect blood glucose level in blood
Correct Answer: B
Rationale: Glucagon causes hyperglycemia by stimulating glycogenolysis and gluconeogenesis in the liver.
A nurse is admitting a client and completing a preassessment before administering medications. Which of the following data should the nurse include in the preassessment? (Select ONE that does not apply.)
- A. Use of herbal teas
- B. Daily fluid intake
- C. Current health status
- D. Previous surgical history
Correct Answer: B
Rationale: Herbal teas , health status , surgical history , and allergies impact medication safety; fluid intake is less critical.