A nurse is caring for an older adult client who has a new prescription for Digoxin and takes multiple other medications. The nurse should recognize that concurrent use of which of the following medications places the client at risk for Digoxin toxicity?
- A. Phenytoin
- B. Verapamil
- C. Warfarin
- D. Aluminum hydroxide
Correct Answer: B
Rationale: Verapamil increases digoxin levels by reducing clearance, risking toxicity.
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Infants and young children are at higher risk of ADRs due to:
- A. Immature renal function in school-age children
- B. Lack of safety and efficacy studies in the pediatric population
- C. Children's skin being thicker than adults, it is less likely to absorb dosages of topical medication
- D. Infant boys having a higher proportion of muscle mass, leading to a higher volume of distribution
Correct Answer: B
Rationale: Lack of pediatric studies increases ADR risk due to unestablished safety/efficacy, unlike renal maturity , skin thickness (C, false), or muscle mass (D, false).
Which is a 5HT-receptor agonist?
- A. Ondansetron
- B. Ketanserine
- C. Sumatriptan
- D. Risperidone
Correct Answer: C
Rationale: Sumatriptan is a 5-HT1D agonist used in migraine.
Which drug(s) would be considered to be in the category Schedule II? (Select all that apply.)
- A. Marijuana
- B. Morphine
- C. Amphetamines
- D. Fiorinal
Correct Answer: C
Rationale: Percodan and amphetamines are Schedule II drugs with high abuse potential. Marijuana is Schedule I, Fiorinal is Schedule III.
A nurse in the post-anesthesia care unit is caring for a client who is experiencing malignant hyperthermia. Which of the following actions should the nurse take?(Select one that does not apply.)
- A. Place a cooling blanket on the client.
- B. Administer oxygen at 100%.
- C. Administer iced 0.9% sodium chloride.
- D. Administer blood, 0.1% sodium chloride.
Correct Answer: D
Rationale: Cooling , oxygen , iced saline , and temperature monitoring manage malignant hyperthermia.
When assessing a patient prior to starting a drug regimen it is often necessary to have a baseline kidney function study done. What might kidney impairment indicate in relation to drug therapy?
- A. Pharmacodynamics stable at the therapeutic dose
- B. Contraindication to the use of a drug
- C. Increased dosage of a drug
- D. Decreased adverse effects of a drug
Correct Answer: B
Rationale: Kidney impairment may contraindicate certain drugs due to reduced clearance, risking toxicity.