Roach's Introductory Clinical Pharmacology 11th Edition - Antihypertensive Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antihypertensive Drugs related questions and content

A nurse is educating a client with hypertension who is prescribed losartan about the drug's action. Which of the following would the nurse incorporate into the teaching about this drug?

  • A. Blocking aldosterone receptors
  • B. Preventing conversion of angiotensin I
  • C. Blocking angiotensin II receptors
  • D. Preventing renin secretion
Correct Answer: C

Rationale: Losartan is an angiotensin II receptor antagonist, acting to block the angiotensin II receptors. By blocking the angiotensin II receptor, the renin-angiotensin system is stopped and consequently blood pressure is reduced. Drugs such as captopril prevent the conversion of angiotensin I. Losartan does not prevent renin secretion. Losartan does not block aldosterone receptors.