A nurse is planning to administer a first dose of Captopril to a client who has hypertension. Which of the following medications can intensify first dose hypotension? (Select one that does not apply.)
- A. Simvastatin
- B. Hydrochlorothiazide
- C. aliskiren
- D. Clonidine
Correct Answer: A
Rationale: Diuretics , clonidine , and aliskiren enhance hypotension with captopril's first dose.
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A nurse is reviewing laboratory findings and notes that a client's plasma Lithium level is 2.1 mEq/L. Which of the following is an appropriate action by the nurse?
- A. Perform immediate gastric lavage.
- B. Prepare the client for hemodialysis.
- C. Administrative and additional oral dose of lithium.
- D. Request a stat repeat of the laboratory test
Correct Answer: B
Rationale: A level of 2.1 mEq/L indicates toxicity (normal 0.6-1.2 mEq/L); hemodialysis is used for severe cases.
The following is the antithyroid mechanism of action of mercazolil:
- A. Inbits thyrotropic hormone production in pituitary
- B. Inhibits thyroid hormone synthesis in thyroid gland
- C. Interfere follicule cells in thyroid gland
- D. Interfere iod reaptake in thyroid gland
Correct Answer: B
Rationale: Mercazolil (methimazole) inhibits thyroid hormone synthesis by blocking thyroperoxidase activity in the thyroid.
The nurse admits a patient to the unit and learns the patient has recently been diagnosed with chronic renal failure but has not informed the primary care provider of this diagnosis. What is the nurse's first priority?
- A. Administer medications ordered immediately.
- B. Maintain the patient's confidentiality.
- C. Call the admitting physician immediately.
- D. Provide teaching about chronic renal failure
Correct Answer: C
Rationale: Renal failure affects drug clearance; informing the physician ensures safe therapy adjustments.
A nurse is providing teaching for a client who has a new prescription for Metformin. Which of the following adverse effects of Metformin should be correct the client to report to the provider?
- A. Somnolence
- B. Constipation
- C. Fluid retention
- D. Weight gain
Correct Answer: A
Rationale: Somnolence could indicate lactic acidosis, a rare but serious metformin side effect to report.
What factor influences drug absorption?
- A. Kidney function
- B. Route of administration
- C. Liver function
- D. Cardiovascular function
Correct Answer: B
Rationale: Drug absorption is influenced by the route of administration. IV administration is the fastest method; drug absorption is slower when given orally. Kidney function impacts excretion, liver function impacts metabolism, and cardiovascular function impacts distribution.
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