Nokea
Angiotensin-converting enzyme inhibitors are useful in a variety of disorders. Which of the following statements are true about both its usefulness in the disorder and the reason for its use?
- A. Stable angina because it decreases the thickening of vascular walls due to decreased modified release.
- B. Heart failure because it reduces remodeling of injured myocardial tissues.
- C. Both 1 and 2 are true and the reasons are correct.
- D. Both 1 and 2 are true but the reasons are wrong.
Correct Answer: B
Rationale: ACE inhibitors reduce myocardial remodeling in heart failure; they are not used for stable angina.
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Which of the following is a disadvantage of IM administration?
- A. Larger volumes can be used
- B. Can affect lab tests
- C. Painful
- D. B and C
Correct Answer: C
Rationale: Intramuscular (IM) administration is painful due to needle insertion, though larger volumes are an advantage; affecting lab tests is less specific, making C the primary disadvantage.
A nurse is reviewing laboratory findings and notes that a client's plasma Lithium level is 2.1 mEq/L. Which of the following is an appropriate action by the nurse?
- A. Perform immediate gastric lavage.
- B. Prepare the client for hemodialysis.
- C. Administrative and additional oral dose of lithium.
- D. Request a stat repeat of the laboratory test
Correct Answer: B
Rationale: A level of 2.1 mEq/L indicates toxicity (normal 0.6-1.2 mEq/L); hemodialysis is used for severe cases.
A patient is prescribed lidocaine for ventricular arrhythmias. Which side effect should the nurse monitor for?
- A. Hypotension
- B. Nausea
- C. Seizures
- D. Bradycardia
Correct Answer: C
Rationale: Lidocaine, a Class IB antiarrhythmic, can cause CNS side effects like seizures at high doses, a key monitoring point.
Which of the following is the mechanism of action of iodides:
- A. Inhibits organification of iodine
- B. By inhibiting \mathrm{Na}+/ \mathrm{l} - simporter reduce iodine transport in thyroid gland
- C. Inhibits production of trioodthyronine form tetraiodthyronine on periphery
- D. Stimulates peroxidase
Correct Answer: A
Rationale: Iodides inhibit iodine organification, reducing thyroid hormone synthesis in high doses.
L-Dopa is
- A. Converted to methyl dopa in the body
- B. Antagonised by riboflavine
- C. Antagonized by nicotinic acid
- D. Combined with carbidopa for enhanced effect
Correct Answer: D
Rationale: Carbidopa enhances L-Dopa's effect by preventing peripheral breakdown.