A nurse is preparing to administer dextrose 5% in water (D5W) 750 mL IV to infuse over 6 hr. The nurse should set the IV pump to deliver how many mL/hr? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 125
- B. 120
- C. 150
- D. 110
Correct Answer: A
Rationale: Calculation: 750 mL ÷ 6 hr = 125 mL/hr, matching the answer.
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The health care provider (HCP) prescribes exenatide (Byetta) for a client with type 1 diabetes mellitus who takes insulin. The nurse knows that which of the following is the appropriate intervention?
- A. The medication is administered within 60 minutes before the morning and evening meal.
- B. The medication is withheld and the HCP is called to question the prescription for the client.
- C. The client is monitored for gastrointestinal side effects after administration of the medication.
- D. The insulin is withdrawn from the Penlet into an insulin syringe to prepare for administration.
Correct Answer: B
Rationale: Exenatide (Byetta) is an incretin mimetic used for type 2 diabetes mellitus only. It is not recommended for clients taking insulin. Hence, the nurse should hold the medication and question the HCP regarding this prescription. Although options 1 and 3 are correct statements about the medication, in this situation the medication should not be administered. The medication is packaged in prefilled pens ready for injection without the need for drawing it up into another syringe.
A nurse is assessing a male client who recently began taking Haloperidol. Which of the following findings is the highest priority to report to the provider?
- A. Shuffling gait
- B. Neck spasms
- C. Drowsiness
- D. Impotence
Correct Answer: B
Rationale: Neck spasms indicate dystonia, an acute extrapyramidal symptom requiring immediate attention.
Vincristine toxicity frequently presents as:
- A. Anemia
- B. Neutropenia
- C. Thrombocytopenia
- D. Polyneuritis
Correct Answer: D
Rationale: Vincristine commonly causes neurotoxicity, including polyneuritis.
The elimination of following drugs is dose dependant except
- A. Phenytoin
- B. Salicylate
- C. Theophylline
- D. Chlorpromazine
Correct Answer: D
Rationale: Chlorpromazine follows first-order kinetics; others exhibit dose-dependent (zero-order) elimination.
Once phosphorylated, the intracellular segment of a receptor tyrosine kinase
- A. Activates adenylate cyclase
- B. Causes dissociation of the ligand from an allosteric binding site
- C. Terminates intracellular signaling cascades
- D. Allows docking of intracellular proteins involved in signal transduction
Correct Answer: D
Rationale: Phosphorylation enables docking of signaling proteins, initiating transduction cascades.