A nurse is providing discharge teaching to a client who has a new prescription for Clozapine. Which of the following statements should the nurse include in the teaching?
- A. You should have a high-carbohydrate snack between meals and at bedtime.
- B. You are likely to develop hand tremors if you take this medication for a long period of time.
- C. You may experience temporary to the first record of the first dose.
- D. You should have your white blood cell count monitored every week.
Correct Answer: D
Rationale: Clozapine requires weekly WBC monitoring due to risk of agranulocytosis.
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Which statement(s) is/are true regarding the types of medication orders? (Select one that does not apply.)
- A. Stat orders are the same as single dose orders.
- B. Verbal orders should be used as much as possible.
- C. Renewal orders facilitate physician review before continuance of high risk medications.
- D. PRN medications will designate a mandatory number of times the medication is to be administered.
Correct Answer: C
Rationale: Standing orders state the frequency of medication dosages to be administered or indicate the time frame of administration. Renewal orders require the physician to review medications that have expired orders, as determined by facility policy. Renewal policies facilitate physician verification of the necessity to continue a medication beyond a usual time frame and help ensure patient safety. Single dose and stat orders are not the same. PRN medications are not ordered a mandatory number of times, although a maximum number might be specified. Verbal orders should be avoided whenever possible.
Hypoglycemic mechanism of biguanides is:
- A. Enhance closure of ATP sensitive K+ channels
- B. Inhibits gluconeogenesis in the liver
- C. Enhance glucose absorption from gastro-intestinal tract
- D. Decrease glycolysis in the peripheral tissue
Correct Answer: B
Rationale: Biguanides like metformin inhibit hepatic gluconeogenesis, reducing blood glucose production.
Which statement accurately describes a drug agonist?
- A. A drug that reacts with specific receptor sites on a cell and prevents the reaction of another chemical with a different receptor site on that cell
- B. A drug that interferes with the enzyme systems that act as catalysts for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with certain receptor sites, preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
Which is not an antithyroid drug?
- A. Mercazolile
- B. Triiodthyronine
- C. Diiodthyrosine
- D. Potassium iodade
Correct Answer: B
Rationale: Triiodothyronine (T3) is a thyroid hormone, not an antithyroid drug, unlike the others which inhibit thyroid function.
The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, This medication is too expensive. Could the doctor order a generic form of this medication? What is the nurse's most accurate response?
- A. Medications are not produced in generic form until the patent expires, which normally takes several years.
- B. You can request the generic form but the binder used may make the drug less effective for this medication.
- C. The generic form of the medication would not be any less expensive because this is a relatively new medication.
- D. Generic medications are lower quality drugs and that would mean you would not be getting the best treatment available.
Correct Answer: A
Rationale: When a new drug enters the market, it is given a time-limited patent; generic forms of the medication cannot be produced until the patent expires. Because no generic version of this drug will exist because it is so new, it is impossible to predict what binder will be used or what the cost would be.
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