Nokea
A nurse is caring for a client who is receiving moderate sedation with Diazepam IV. The client is oversedated. Which of the following medications should the nurse anticipate administering to this client?
- A. Ketamine
- B. Naltrexone
- C. Flumazenil
- D. Fluvoxamine
Correct Answer: C
Rationale: Flumazenil reverses benzodiazepine oversedation, like diazepam.
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A patient who has chronic liver disease reports contact with a person who has tuberculosis (TB). The nurse will counsel this patient to contact the provider to discuss
- A. a chest x-ray
- B. a TB skin test
- C. liver function tests (LFTs)
- D. prophylactic antitubercular drugs
Correct Answer: B
Rationale: TB exposure requires a skin test first; chest x-ray follows if positive, and LFTs or prophylaxis aren't initial steps. Patients who have exposure to TB should have a TB skin test.
Idiosyncrasy is:
- A. A genetically determined abnormal reaction to drugs
- B. A characteristic toxic effect at therapeutic doses
- C. An altered physiological state produced by repeated drug use
- D. An immunologically mediated reaction
Correct Answer: A
Rationale: Idiosyncrasy is a genetically determined unusual response to a drug, e.g., G6PD deficiency with primaquine.
Which statement accurately describes a drug agonist?
- A. A drug that reacts with specific receptor sites on a cell and prevents the reaction of another chemical with a different receptor site on that cell
- B. A drug that interferes with the enzyme systems that act as catalysts for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with certain receptor sites, preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
Thyroxin is contributed in all listed processes except one:
- A. Increase tissue demand of oxygen consumption
- B. Activating protein, carbohydrates and fats metabolism
- C. Increase the main metabolism
- D. Decrease the main metabolism
Correct Answer: D
Rationale: Thyroxine (T4) increases metabolism, not decreases it, by enhancing oxygen use and nutrient breakdown.
You are designing a drug regimen for a patient. What should be considered?
- A. Quality-of-life issues
- B. Ethnicity of patient
- C. Gender
- D. Quantity-of-life issues
Correct Answer: A
Rationale: Quality-of-life issues ensure the regimen aligns with patient needs and tolerability, enhancing adherence.