The nurse is caring for a patient scheduled for surgery this morning who is not to be given anything orally. The nurse reviews the medication administration record and finds the patient has an important medication due but it is supposed to be given orally. What is the nurse's best action?
- A. Give the medication with a small sip of water.
- B. Give the medication via a different route.
- C. Hold the medication and put a note on the front of the chart for the surgeon.
- D. Call the ordering health care provider and clarify administration
Correct Answer: D
Rationale: NPO status requires physician clarification to ensure safety and appropriateness of administration.
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The volume of distribution (Vd) for a drug that is completely retained in the vascular compartment would be?
- A. High
- B. Low
- C. Unchanged
- D. Cannot be determined
Correct Answer: B
Rationale: A drug confined to the vascular compartment (e.g., plasma) has a low Vd, close to plasma volume (about 0.06 L/kg), indicating limited distribution.
Which aminoglycoside is most commonly used in the treatment of cystic fibrosis patients infected with Pseudomonas aeruginosa?
- A. Amikacin
- B. Streptomycin
- C. Tobramycin
- D. Gentamicin
Correct Answer: C
Rationale: Tobramycin is frequently used in cystic fibrosis patients for its efficacy against Pseudomonas aeruginosa, often administered via inhalation or IV.
Which of the following is biguanide:
- A. Glibenclamide
- B. Metformin
- C. Acarbose
- D. Liraglutide
Correct Answer: B
Rationale: Metformin is a biguanide that reduces hepatic glucose output.
A nurse is assessing a client's IV infusion site. Which of the following findings should the nurse identify as an indication of phlebitis?
- A. Factor
- B. Darkness
- C. Erythema
- D. Coolness
Correct Answer: C
Rationale: Erythema and pain are classic signs of phlebitis, inflammation of the vein.
You are designing a drug regimen for a patient. What should be considered?
- A. Quality-of-life issues
- B. Ethnicity of patient
- C. Gender
- D. Quantity-of-life issues
Correct Answer: A
Rationale: Quality-of-life issues ensure the regimen aligns with patient needs and tolerability, enhancing adherence.
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