Nokea
Which is not an antithyroid drug?
- A. Mercazolile
- B. Triiodthyronine
- C. Diiodthyrosine
- D. Potassium iodade
Correct Answer: B
Rationale: Triiodothyronine (T3) is a thyroid hormone, not an antithyroid drug, unlike the others which inhibit thyroid function.
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Vera, age 70, has isolated systolic hypertension. Calcium channel blocker dosages for her should be:
- A. Started at about half the usual dosage
- B. Not increased over the usual dosage for an adult
- C. Given once daily because of memory issues in the older adult
- D. Withheld if she experiences gastroesophageal reflux
Correct Answer: A
Rationale: Elderly patients start at half dose due to reduced metabolism and clearance.
Hypoglycemic mechanism of biguanides is:
- A. Enhance closure of ATP sensitive K+ channels
- B. Inhibits gluconeogenesis in the liver
- C. Enhance glucose absorption from gastro-intestinal tract
- D. Decrease glycolysis in the peripheral tissue
Correct Answer: B
Rationale: Biguanides like metformin inhibit hepatic gluconeogenesis, reducing blood glucose production.
Drug which interferes with metabolism of theophylline is:
- A. Erythromycin
- B. Gentamicin
- C. Penicillin
- D. Furazolidone
Correct Answer: A
Rationale: Erythromycin inhibits P-450, increasing theophylline levels.
Patrick is a 10-year-old patient who presents with uncomfortable constipation. Along with diet changes, a laxative is ordered to provide more rapid relief of constipation. An appropriate choice of medication for a 10-year-old child would be:
- A. PEG 3350 (Miralax)
- B. Bisacodyl (Dulcolax) suppository
- C. Docusate (Colace) suppository
- D. Polyethylene glycol electrolyte solution
Correct Answer: A
Rationale: PEG 3350 is safe and effective for kids; suppositories (B, C) are less preferred, and PEG solution is for bowel prep.
Howard is a 72-year-old male who occasionally takes diphenhydramine for his seasonal allergies. Monitoring for this patient taking diphenhydramine would include assessing for:
- A. Urinary retention
- B. Cardiac output
- C. Peripheral edema
- D. Skin rash
Correct Answer: A
Rationale: Diphenhydramine , an antihistamine, has anticholinergic effects that can cause urinary retention, especially in older males; other effects are less common.