Nokea
A nurse is caring for a group of clients who are not protected against Varicella. The nurse should prepare to administer the Varicella vaccine at this time to which of the following clients?
- A. 24-year-old woman in the third trimester of pregnancy
- B. 12-year-old child who has a severe allergy to neomycin
- C. 2-month-old infant who has no health problems
- D. 32-year-old man who has essential hypertension
Correct Answer: D
Rationale: Varicella vaccine is safe for the 32-year-old ; it's contraindicated in pregnancy, neomycin allergy, and infants under 1 year.
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The volume of distribution (Vd) for a drug that is completely retained in the vascular compartment would be?
- A. High
- B. Low
- C. Unchanged
- D. Cannot be determined
Correct Answer: B
Rationale: A drug confined to the vascular compartment (e.g., plasma) has a low Vd, close to plasma volume (about 0.06 L/kg), indicating limited distribution.
Thyroxin is contributed in all listed processes except one:
- A. Increase tissue demand of oxygen consumption
- B. Activating protein, carbohydrates and fats metabolism
- C. Increase the main metabolism
- D. Decrease the main metabolism
Correct Answer: D
Rationale: Thyroxine (T4) increases metabolism, not decreases it, by enhancing oxygen use and nutrient breakdown.
A patient receiving gentamicin should be monitored for which potential adverse effect?
- A. Nephrotoxicity
- B. Hepatotoxicity
- C. Ototoxicity
- D. Both A and C
Correct Answer: D
Rationale: Gentamicin, an aminoglycoside, commonly causes nephrotoxicity and ototoxicity , requiring monitoring of renal function and hearing.
The nurse is helping a client review a prescription from the health care provider. When examining the prescription, which of the following would the nurse expect to find documented?
- A. Name of the drug
- B. Dosage of the drug
- C. Route of drug administration
- D. All the above
Correct Answer: D
Rationale: The prescription must contain the client's name, the name of the drug, the dosage, the method and times of administration, and the signature of the licensed health care provider prescribing the drug.
Which of the following is biguanide:
- A. Glibenclamide
- B. Metformin
- C. Acarbose
- D. Liraglutide
Correct Answer: B
Rationale: Metformin is a biguanide that reduces hepatic glucose output.