A nurse is providing instructions to a female client who has a new prescription for Zolpidem. Which of the following instructions should the nurse include?
- A. Notify the provider if you plan to become pregnant.
- B. Take the medication 1 hr before you plan to go to sleep.
- C. Allow at least 6 hr for sleep when taking zolpidem.
- D. To increase the effectiveness of zolpidem, take it with a bedtime snack.
Correct Answer: A
Rationale: Pregnancy notification is key due to zolpidem's risks; it's taken just before sleep, needing 7-8 hours.
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The nurse caring for a patient who has tuberculosis and who is taking isoniazid, rifampin, and streptomycin reviews the medical record and notes the patient's sputum cultures reveal resistance to streptomycin. The nurse will expect the provider to order which drug?
- A. Isoniazid (INH)
- B. Pyrazinamide
- C. Rifampin (Rifadin)
- D. Streptomycin
Correct Answer: A
Rationale: INH is the prophylactic standard for TB contacts; other drugs aren't typically used alone for this. INH is the drug of choice for prophylactic treatment of patients who have had close contact with a patient who has tuberculosis.
The nurse is preparing to administer Lanoxin to a patient on the telemetry unit. In addition to understanding the patient's diagnosis, the nurse must also know which characteristic(s) of the medication?(Select one that does not apply.)
- A. Chemical composition
- B. Adverse effects
- C. Expected actions
- D. Contraindications for use
Correct Answer: A
Rationale: The nurse must understand the individual patient's diagnosis and symptoms that correlate with the rationale for drug use. The nurse should also know why a medication is ordered, expected actions, usual dosing, proper dilution, route and rate of administration, adverse effects, and contraindications for the use of a particular drug. It is not required that the nurse know the chemical composition of the medication prior to administration.
Several classes of drugs have interactions with cholinergic blockers. Which of the following is true about these interactions?
- A. Drugs with a narrow therapeutic range given orally may not stay in the GI tract long enough to produce an action.
- B. Additive antimuscarinic effects may occur with antihistamines.
- C. Cholinergic blockers may decrease the sedative effects of hypnotics.
- D. Cholinergic blockers are contraindicated with antipsychotics.
Correct Answer: B
Rationale: Additive antimuscarinic effects with antihistamines can enhance side effects like sedation.
Alcohol should not be given with
- A. Sulphonamides
- B. Clonidine
- C. Reserpine
- D. Metronidazole
Correct Answer: D
Rationale: Metronidazole with alcohol causes a disulfiram-like reaction (flushing, nausea).
Which of the following class of agonists can precipitate hyperglycemia in diabetics?
- A. a 1-agonists
- B. α2-agonists
- C. β1-agonists
- D. β2-agonists
Correct Answer: D
Rationale: Beta-2 agonists (e.g., salbutamol) increase glycogenolysis, raising blood glucose.
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