Nokea
A nurse is providing teaching to a client who has a new prescription for Buspirone to treat Anxiety. Which of the following information should the nurse include?
- A. Take this medication on an empty stomach
- B. Expect optimal therapeutic effects within 24 hr.
- C. Take this medication when needed for anxiety
- D. This medication has a low risk for dependency.
Correct Answer: D
Rationale: Buspirone has a low dependency risk , unlike benzodiazepines; it takes weeks to work, not PRN.
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The following class of drugs may be used to treat Parkinsonian syndrome arising from the use of phenothiazines:
- A. Nicotinic receptor antagonists
- B. Muscarinic receptor antagonists
- C. Adrenoceptor antagonists
- D. Anticholinesterases
Correct Answer: B
Rationale: Antimuscarinics (e.g., benztropine) relieve parkinsonism from phenothiazines.
Dwayne has recently started on carbamazepine to treat seizures. He comes to see you and you note that while his carbamazepine levels had been in the therapeutic range, they are now low. The possible cause for the low carbamazepine levels include:
- A. Dwayne hasn't been taking his carbamazepine because it causes insomnia.
- B. Carbamazepine auto-induces metabolism, leading to lower levels in spite of good compliance.
- C. Dwayne was not originally prescribed the correct amount of carbamazepine.
- D. Carbamazepine is probably not the right antiseizure medication for Dwayne.
Correct Answer: B
Rationale: Carbamazepine induces its own metabolism (auto-induction), reducing levels over time.
The drug, which interferes with metabolism of theophylline
- A. Gentamicin
- B. Penicillin
- C. Erythromycin
- D. Sulfonamide
Correct Answer: C
Rationale: Erythromycin inhibits cytochrome P-450, reducing theophylline metabolism.
The client with acute myelocytic leukemia is being treated with busulfan (Myleran). Which laboratory value would the nurse specifically monitor during treatment with this medication?
- A. Clotting time
- B. Uric acid level
- C. Potassium level
- D. Blood glucose level
Correct Answer: B
Rationale: Busulfan (Myleran) can cause an increase in the uric acid level. Hyperuricemia can produce uric acid nephropathy, renal stones, and acute renal failure. Options 1, 3, and 4 are not specifically related to this medication.
Because of the pattern of cholesterol synthesis, reductase inhibitors are given:
- A. In the evening in a single daily dose
- B. Twice daily in the morning and the evening
- C. With each meal and at bedtime
- D. In the morning before eating
Correct Answer: A
Rationale: Cholesterol synthesis peaks at night, so evening dosing optimizes reductase inhibitor efficacy.