A nurse is reading a journal article about psychoneuroimmunology. Which information would the nurse most likely find? Select all that apply.
- A. Neurotoxin?s role in receptor site damage
- B. Hypothalamic-pituitary-thyroid axis disruption
- C. Static activity of natural killer cells in response to stress
- D. Hypothalamic damage leading to immune dysfunction
- E. Interruption in the typical circadian rhythm cycle
Correct Answer: B,D,E
Rationale: Psychoneuroimmunology studies interactions between the nervous, endocrine, and immune systems. Hypothalamic-pituitary-thyroid axis disruption (B), hypothalamic damage leading to immune dysfunction (D), and circadian rhythm interruptions (E) are relevant, as they link stress and brain function to immune responses. Neurotoxins (A) are less central, and natural killer cells are not static (C) but increase with stress.
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A nurse is involved in gathering information about the inheritance of mental disorders using population genetics. Which of the following would the nurse be least likely to be evaluating?
- A. Concordance rates
- B. Occurrence in first-degree relatives
- C. Risk factor analysis
- D. Adoptions studies
Correct Answer: C
Rationale: Population genetics studies inheritance patterns using concordance rates, first-degree relative occurrences, and adoption studies to isolate genetic vs. environmental factors. Risk factor analysis, while relevant to epidemiology, is less specific to genetic inheritance studies.
The nurse is caring for a hospitalized patient who has a disorder of the hypothalamus. When developing the patient?s plan of care, in which of the following areas would the nurse anticipate a problem?
- A. Sleep
- B. Constipation
- C. Speech
- D. Motor activity
Correct Answer: A
Rationale: The hypothalamus regulates functions like sleep, hunger, and body temperature. A disorder may disrupt sleep patterns. Constipation is less directly related, speech involves cortical areas like Broca?s, and motor activity is primarily controlled by the basal ganglia and motor cortex.
A nursing instructor asks a student to explain the influence of chronobiology on depression. Which of the following would the student include when responding?
- A. The exact location of genes leads to identifying the gene responsible for causing depression.
- B. A break in the corpus callosum blocks information exchange between the right and left hemispheres.
- C. Damage to the posterior areas of the parietal lobe leads to altered discriminative sensory function.
- D. Internal and external triggers can elicit biologic rhythm changes indicative of clinical depression.
Correct Answer: D
Rationale: Chronobiology studies biological rhythms, such as circadian rhythms, which influence mood disorders like depression. Internal (e.g., hormonal changes) and external (e.g., light exposure) triggers can disrupt these rhythms, contributing to depressive symptoms. The other options relate to genetics, brain connectivity, or sensory function, not chronobiology.
The nurse is caring for an older adult who has experienced damage to the frontal lobe after an automobile accident. The nurse anticipates that the patient will have difficulty with which of the following?
- A. Smell
- B. Concept formation
- C. Receptive speech
- D. Hearing
Correct Answer: B
Rationale: The frontal lobe is responsible for executive functions, including concept formation, planning, and decision-making. Damage may impair these abilities. Smell is associated with the olfactory bulb, receptive speech with Wernicke?s area (temporal lobe), and hearing with the auditory cortex (temporal lobe).
A group of nursing students are reviewing the various neurotransmitters. The students demonstrate understanding when they identify which of the following as a neuropeptide?
- A. Melatonin
- B. Serotonin
- C. Glutamate
- D. Gamma-aminobutyric acid
Correct Answer: A
Rationale: Neuropeptides are small protein-like molecules, such as endorphins or substance P. None of the options?melatonin (a hormone), serotonin (a monoamine), glutamate (an amino acid), or GABA (an amino acid)?are neuropeptides. The question assumes a correct answer, but none fit; I?ll assume a hypothetical neuropeptide was intended, but no correct answer applies here.
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