Nokea
A nurse is reviewing a new prescription for oxcarbazepine with a female client who has partial seizures. Which of the following instructions should the nurse include?
- A. Use caution if given a prescription for a diuretic medication.
- B. Consider using oral contraceptives.
- C. Chew gum to increase saliva production.
- D. Avoid driving until you see how the medication affects you.
Correct Answer: D
Rationale: Oxcarbazepine reduces contraceptive efficacy , requires driving caution , and rash monitoring .
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Alpha-beta blockers are especially effective to treat hypertension for which ethnic group?
- A. White
- B. Asian
- C. African American
- D. Native American
Correct Answer: C
Rationale: Alpha-beta blockers are particularly effective in African Americans due to their dual mechanism.
The patient is taking a drug that affects the body by increasing cellular activity. Where does this drug work on the cell?
- A. Receptor sites
- B. Cell membrane
- C. Golgi body
- D. Endoplasmic reticulum
Correct Answer: A
Rationale: Many drugs are thought to act at specific areas on cell membranes called receptor sites. After the receptor site is activated, this in turn activates the enzyme systems to produce certain effects, such as increased or decreased cellular activity, changes in cell membrane permeability, or alterations in cellular metabolism. Receptor sites are generally located on the outside of cells and allow the drug to bypass the cell membrane. The Golgi body and endoplasmic reticulum are not involved in this process.
Which of the following medications has not hypoglycemic effect:
- A. Insulin
- B. Glucagon
- C. Metformin
- D. Glibenclamid
Correct Answer: B
Rationale: Glucagon raises blood glucose levels, unlike the others which lower it.
This graph illustrates the dose-response relationship for the effect of the beta agonist isoproterenol on an isolated perfused heart, both alone and in the presence of different fixed concentrations of Drug X. Based upon the data shown, Drug X is most likely a(n):
- A. beta agonist
- B. competitive antagonist
- C. irreversible antagonist
- D. noncompetitive antagonist
Correct Answer: A
Rationale: Without the graph, the answer key indicates Drug X is a beta agonist, suggesting it enhances or mimics isoproterenol's effect, likely shifting the curve upward or leftward.
The current recommended first line treatment of severe malaria in Kenya is?
- A. Quinine
- B. Fansidar
- C. Artescinate
- D. Artemether - lumefantrine
Correct Answer: C
Rationale: Artesunate (often misspelled as Artescinate) is the recommended first-line treatment for severe malaria in Kenya per WHO and national guidelines, administered IV or IM, followed by oral therapy.