A nurse is teaching a client who has a new prescription for Baclofen to treat muscle spasms. Which of the following statements by the client indicates an understanding of the teaching?(Select one that does not apply.)
- A. I will stop taking this medication right away if I develop dizziness.
- B. I know the doctor will gradually increase my dose of this medication for a while.
- C. I should increase fiber to prevent constipation from this medication.
- D. I won't be able to drink alcohol while I'm taking this medication.
Correct Answer: A
Rationale: Gradual dosing , fiber for constipation , and no alcohol reflect baclofen teaching; stopping for dizziness is incorrect.
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The patient is taking a 2-mg dose of ropinerol XR. The drug has a half-life of 12 hours. How long will it be before only 0.25 mg of this drug remains in the patient's system?
- A. 24 hours
- B. 36 hours
- C. 48 hours
- D. 60 hours
Correct Answer: B
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved. At 12 hours there will be 1 mg of the drug available to the body. At 24 hours there will be 0.5 mg, at 36 hours there will be 0.25 mg, at 48 hours there will be 0.125 mg, and at 60 hours there will be 0.0625 mg.
A group of nursing students are reviewing information about drug development in the United States in preparation for an exam. The students demonstrate understanding of this material when they identify testing of which of the following as one of the first steps?
- A. Small group of healthy volunteers
- B. People who have the disease
- C. Live animals
- D. Large numbers of patients
Correct Answer: C
Rationale: Initially, drug testing begins with testing in an artificial environment such as a test tube, and then this testing is followed by testing on live animals. Next, clinical testing occurs with each phase involving a larger number of people. First, a small group of 20 to 100 healthy volunteers are tested; then testing is performed on people who have the disease or condition. Last, the drug is given to large numbers of patients in medical research centers.
In post menopausal women who are receiving estrogen replacement therapy, medroxyprogesterone is administered concurrently to reduce the risk of:
- A. Atherosclerosis
- B. Endometrial cancer
- C. Hypertension
- D. Osteoporosis
Correct Answer: B
Rationale: Progestins like medroxyprogesterone reduce estrogen-induced endometrial hyperplasia and cancer risk.
A nurse is caring for a client who has a new prescription for Valproic Acid. The nurse should instruct the client that while taking this medication he will need to have which of the following laboratory tests completed periodically?
- A. Thrombocyte count
- B. Hematocrit
- C. Amylase
- D. Kidney function tests
Correct Answer: A
Rationale: Valproic acid requires monitoring of platelets for bleeding risk and liver function for hepatotoxicity.
Patient education regarding taking iron replacements includes:
- A. Doubling the dose if they miss a dose to maintain therapeutic levels
- B. Taking the iron with milk or crackers if it upsets their stomach
- C. Iron is best taken on an empty stomach with juice
- D. Antacids such as Tums may help the upset stomach caused by iron therapy
Correct Answer: C
Rationale: Iron absorption is best on an empty stomach with juice; milk or antacids reduce absorption, and doubling risks toxicity.
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