Nokea
A nurse is working as part of a team involved with the testing of a new psychiatric medication. The drug is currently being used in multiple clinical trials at various different sites. The nurse is engaged in which phase of testing?
- A. Phase I
- B. Phase II
- C. Phase III
- D. Phase IV
Correct Answer: C
Rationale: Phase III clinical trials involve testing a drug in multiple sites with larger populations to confirm efficacy and safety, matching the scenario. Phase I tests safety in small groups, Phase II assesses efficacy in a limited population, and Phase IV occurs post-market.
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After teaching a patient who is prescribed imipramine about the drug, the nurse determines that the teaching was effective when the patient states which of the following?
- A. I need to be careful because the drug can make me sleepy.
- B. I don?t have to worry about getting dizzy when I get up from lying down.
- C. I might notice some excess saliva in my mouth at different times.
- D. I need to avoid foods with fiber because diarrhea can occur.
Correct Answer: A
Rationale: Imipramine, a tricyclic antidepressant, commonly causes sedation, so the patient?s statement about sleepiness indicates effective teaching. Dizziness (orthostatic hypotension) is a concern, dry mouth (not excess saliva) is typical, and constipation (not diarrhea) is a side effect, making other options incorrect.
A group of nursing students are reviewing the various drug classes used to treat psychiatric disorders. The students demonstrate understanding when they identify which of the following as examples of antianxiety medications? Select all that apply.
- A. Selegiline
- B. Lorazepam
- C. Buspirone
- D. Zolpidem
- E. Methylphenidate
Correct Answer: B,C
Rationale: Lorazepam (B), a benzodiazepine, and buspirone (C), a non-benzodiazepine, are antianxiety medications. Selegiline is an MAOI, zolpidem is a sedative-hypnotic, and methylphenidate is a stimulant, not used for anxiety.
A patient with depression asks the nurse about possible herbal supplements. Which of the following would the nurse identify as being commonly used?
- A. Valerian
- B. St. John?s wort
- C. Kava
- D. Melatonin
Correct Answer: B
Rationale: St. John?s wort is commonly used for mild to moderate depression due to its serotonergic effects. Valerian and melatonin are used for sleep, and kava for anxiety, not primarily for depression.
After teaching a patient who is receiving phenelzine, the nurse determines that the teaching was successful when the patient states the need to avoid which of the following?
- A. Fresh cottage cheese
- B. Cooked sliced ham
- C. Tap beers
- D. Soy milk
Correct Answer: C
Rationale: Phenelzine, an MAOI, requires avoiding tyramine-rich foods and drinks like tap beers, which can cause a hypertensive crisis. Fresh cottage cheese, cooked ham, and soy milk are generally safe, as they have low tyramine content.
A group of nursing students are reviewing information related to drug therapy for mood disorders. The students demonstrate understanding of the information when they identify which agent as the gold standard for treating bipolar disorder?
- A. Carbamazepine
- B. Lithium
- C. Valproate
- D. Lamotrigine
Correct Answer: B
Rationale: Lithium is the gold standard for bipolar disorder due to its proven efficacy in stabilizing mood and preventing manic episodes. Carbamazepine, valproate, and lamotrigine are used but are not considered the primary standard.