A nurse should advise clients taking which medications to avoid the use of ginkgo?
- A. Selective serotonin reuptake inhibitors
- B. Monoamine oxidase inhibitors
- C. NSAIDs
- D. Nonsalicylates
- E. Anticholinergics
Correct Answer: A,B
Rationale: Ginkgo is contraindicated in clients taking SSRI or MAOI antidepressants, because of the risk of a toxic reaction. Cholinesterase inhibitors interact with anticholinergics. Ginkgo does not interact with NSAIDs or nonsalicylates.
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A nurse is caring for a client receiving donepezil for treatment of Alzheimer's disease. Which of the following factors should the nurse monitor when assessing the client before administering the drug?
- A. Sexual habits
- B. Body weight
- C. Sleeping patterns
- D. Eating habits
Correct Answer: B
Rationale: The nurse should monitor body weight and the vital signs of the client during the initial assessment. The nurse need not monitor the sexual habits, sleeping patterns, or eating habits of the client when administering cholinesterase inhibitors.
A caregiver of a client diagnosed with AD asks the nurse about the cholinesterase inhibitor galantamine prescribed for the client. Which response by the nurse would be most appropriate?
- A. The drug will help to cure the memory problems the client is experiencing.
- B. Once the symptoms improve, the drug will most likely be stopped.
- C. These drugs help to slow the progression of the disease.
- D. This drug is primarily given to control the delirium the client is experiencing.
Correct Answer: C
Rationale: The progression of memory loss associated with dementia is treated with cholinesterase inhibitors. These drugs slow progression but do not cure dementia. These drugs are given to clients with mild to moderate dementia, but they do not treat any delirium that the clients may experience. Cholinesterase inhibitors are not frequently used in late-stage AD.
A nurse is preparing to administer rivastigmine oral solution. The nurse decides to mix it in a small amount of which of the following?
- A. Water
- B. Coffee
- C. Soda
- D. Tea
- E. Fruit juice
Correct Answer: A,C,E
Rationale: A nurse administering rivastigmine (Exelon) oral solution can give the solution directly to the client or mix it in a small amount of water, cold fruit juice, or soda.
A nurse is reviewing the action of memantine. The nurse understands that this drug addresses which of the following?
- A. Acetylcholine
- B. Glutamate
- C. Serotonin
- D. Dopamine
Correct Answer: B
Rationale: Memantine, an NMDA receptor antagonist, is thought to work by decreasing the excitability of neurotransmission caused by an excess of the amino acid glutamate in the CNS.
A client with AD is prescribed rivastigmine by the primary health care provider. The nurse would anticipate administering this drug by which route?
- A. Intravenously
- B. Intramuscularly
- C. Orally
- D. Subcutaneously
- E. Transdermally
Correct Answer: C,E
Rationale: The nurse should administer rivastigmine orally or transdermally to the client. Rivastigmine is not administered intravenously, intramuscularly, or subcutaneously.
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