Roach's Introductory Clinical Pharmacology 11th Edition - Antibacterial Drugs That Interfere With Protein Synthesis Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antibacterial Drugs That Interfere With Protein Synthesis related questions and content

A nurse suspects that a patient receiving an aminoglycoside is developing neurotoxicity based on assessment of which of the following? Select all that apply.

  • A. Paresthesias
  • B. Tingling around the mouth
  • C. Ringing in the ears
  • D. Vertigo
Correct Answer: A, B, E

Rationale: Signs and symptoms of neurotoxicity include numbness, skin tingling, circumoral (around the mouth) paresthesia, peripheral paresthesia, tremors, muscle twitching, convulsions, muscle weakness, and neuromuscular blockade (acute muscular paralysis and apnea). Ringing in the ears and vertigo would suggest ototoxicity.