Nokea
A nurse understands that the antidepressant drug paroxetine (Paxil) can be used to treat which of the following medical conditions?
- A. Enuresis
- B. Depressive episodes
- C. Anorexia
- D. Obsessive-compulsive disorders
- E. Bulimia nervosa
Correct Answer: B,D,E
Rationale: Paroxetine, an SSRI, is indicated for depressive episodes, obsessive-compulsive disorder, and bulimia nervosa due to its serotonin-modulating effects.
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When describing the action of antidepressants, the nursing instructor would include the belief that they exert their effect by causing slow adaptive changes to which of the following receptor systems?
- A. Beta-adrenergic
- B. Baroreceptors
- C. Norepinephrine
- D. Serotonin
- E. Nicotinic
Correct Answer: C,D
Rationale: Antidepressants, particularly those affecting monoamine systems, induce adaptive changes in norepinephrine and serotonin receptor systems, enhancing neurotransmission over time.
A client is prescribed lithium. The nurse suspects lithium toxicity based on which lithium drug level?
- A. 0.8mEq /L
- B. 1.0mEq /L
- C. 1.3mEq /L
- D. 1.6mEq /L
Correct Answer: D
Rationale: Lithium toxicity typically occurs at serum levels above 1.5 mEq/L, making 1.6 mEq/L indicative of toxicity.
The nurse suspects that a client is experiencing major depression based on assessment of which of the following?
- A. Feelings of hopelessness
- B. Minimal changes in weight
- C. Focused concentration
- D. Loss of energy
- E. Excessive guilt
Correct Answer: A,D,E
Rationale: Major depression is characterized by hopelessness, loss of energy, and excessive guilt, which are core diagnostic symptoms.
A group of nursing students are reviewing information about antidepressants. The students demonstrate understanding of the information when they identify which of the following as an example of a serotonin/norepinephrine and dopamine/norepinephrine reuptake inhibitor?
- A. Doxepin
- B. Venlafaxine
- C. Bupropion
- D. Sertraline
- E. Escitalopram
Correct Answer: B,C
Rationale: Venlafaxine and bupropion inhibit reuptake of serotonin, norepinephrine, and/or dopamine, distinguishing them from other antidepressants.
A client receiving clomipramine is given a prescription for zolpidem for sleep. The primary health care provider was unaware the client was taking clomipramine. Which of the following reactions might the nurse observe in this client?
- A. Respiratory depression
- B. CNS depression
- C. Hypertensive crisis
- D. Easy bruising
- E. Hyperglycemia
Correct Answer: A,B
Rationale: Combining clomipramine with zolpidem increases the risk of respiratory and CNS depression due to additive sedative effects.