Roach's Introductory Clinical Pharmacology 11th Edition - Cardiotonic and Inotropic Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Cardiotonic and Inotropic Drugs related questions and content

A nursing instructor is conducting a class on heart failure and the events that occur. The instructor describes which of the following as a result of increases in neurohormonal activity that occur with heart failure? Select all that apply.

  • A. Decreased secretion of catecholamines
  • B. Remodeling of the cardiac muscle cells
  • C. Hypertrophy of the heart
  • D. Increased need for oxygen
  • E. Cardiac necrosis
Correct Answer: B,C,D,E

Rationale: Increased catecholamines lead to increases in neurohormonal activity that cause remodeling of the cardiac muscle cells, leading to hypertrophy of the heart, increased need for oxygen, and cardiac necrosis, which worsen the heart failure.