Roach's Introductory Clinical Pharmacology 11th Edition - Upper Respiratory System Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Upper Respiratory System Drugs related questions and content

A nursing instructor is describing the advantages of using a second-generation antihistamine over a first-generation antihistamine. Which of the following would the instructor most likely include? Select all that apply.

  • A. Less sedation
  • B. Fewer anticholinergic effects
  • C. Less nausea
  • D. Can be used during pregnancy
  • E. Can be used during lactation
Correct Answer: A,B

Rationale: Second-generation antihistamines cause less sedation and fewer anticholinergic effects because they selectively bind to peripheral rather than central H1 receptors. Some first-generation antihistamines can be used as antiemetics. Use of any antihistamine is contraindicated during pregnancy and lactation.